阿司匹林对木糖葡萄球菌体外生物被膜的作用  

Effect of aspirin against Staphylococcus xylosus biofilm in vitro

作　　者：徐长赓 周永辉[1] 杨艳北[1] 郝美琪 陈俭清[1] 李艳华[1] 

机构地区：[1]东北农业大学动物医学学院,黑龙江哈尔滨150030

出　　处：《中国兽医杂志》2016年第6期33-35,38,共4页Chinese Journal of Veterinary Medicine

基　　金：国家自然科学基金(GA15B201)

摘　　要：通过阿司匹林对木糖葡萄球菌生物被膜干预作用的研究,为木糖葡萄球菌生物被膜的治疗提供理论参考。通过结晶紫染色法(CV)、XTT分析法和激光共聚焦显微镜方法研究阿司匹林对木糖葡萄球菌生物被膜的作用及生物被膜下活菌和死菌的分布情况。结果显示,阿司匹林对木糖葡萄球菌有抑菌作用并且对其生物被膜的干预作用显著。Aspirin against Staphylococcus xylose biofilm showed that it could be provide a new therapeutic approach for the in-fection caused by biofilm. The effect of aspirin against Staphylococcus xylose biofilm was assessed by the crystal violet staining（CV）.The bacteria activity under the mature biofilm was used to measure by XTT and CLSM.The results indicated that aspirin in-hibited the growth of bacterial and had a significant impact on Staphylococcus xylose biofilm（P0.05）.Our data show that,the as-pirin on Staphylococcus xylosus biofilm has a significant intervention effect.

关 键 词：阿司匹林 木糖葡萄球菌生物被膜 结晶紫染色法 激光共聚焦显微镜 XTT分析法 

分 类 号：R96[医药卫生—药理学]