急诊重型颅脑损伤患者咪达唑仑诱导气管插管的效果分析  

Efficacy Analysis of Tracheal Intubation Induced by Midazolam in Patients with Acute Severe Brain Injury

作　　者：洪海斌[1] 黄之抗[1] 庄炯宇[1] 李海忠[1] 蔡家骥[1] 

机构地区：[1]广东省中山市博爱医院,528403

出　　处：《岭南急诊医学杂志》2016年第3期228-229,共2页Lingnan Journal of Emergency Medicine

摘　　要：目的:总结急诊重型颅脑损伤患者咪达唑仑诱导气管插管的效果。方法:回顾性分析2013年1月-2015年12月我院急诊救治的96例重型颅脑损伤患者的临床资料,按麻醉方案不同分为对照组(n=40)和研究组(n=56),对照组行地西泮麻醉,研究组行咪达唑仑麻醉,比较两组插管即刻生命体征及插管后连接呼吸机前血气分析情况。结果:研究组平均动脉压(MAP)、呼吸频率(RR)、心率(HR)、血氧分压(PaO_2)及二氧化碳分压(PaCO_2)均显著优于对照组(P<0.05)。结论 :急诊重型颅脑损伤患者使用咪达唑仑镇静行气管插管术较地西泮能更有效减轻气管插管时的心血管反应,而对呼吸功能几乎无影响。Objective ： To summarize effect of tracheal intubation induced by midazolam in patients with acute severe brain injury. Methods ：The clinical data of 96 patients with acute severe brain injury were retrospectively analyzed from Jan 2013 to Dec 2015,and the cases were divided into control group（n =40） and research group（n =56） anesthetized by diazepam and midazolam respectively,the vital signs after intubation and before connecting the ventilator gas analysis situation were compared between the two groups. Results ：The mean arterial pressure（MAP）,respiratory rate（RR）, heart rate（HR）, blood oxygen pressure（PaO_2） and carbon dioxide partial pressure（PaCO_2）in research group were significantly better than those in the control group（all P〈0.05）. Conclusion ：Compared with diazepam,it is more effective in reducing cardiovascular response and almost no impact on the respiratory function in patients with acute severe brain injury tracheal intubation induced by midazolam.

关 键 词：咪达唑仑 重型颅脑损伤 气管插管 效果 

分 类 号：R651.15[医药卫生—外科学]