浓盐水加甲硝唑坐浴治疗白血病肛周感染的效果观察  

Effects of high-concentrated brine with metronidazole sitz bath on the treatment of perianal inflammation in leukemia patients

作　　者：姚晓丹[1] 王莉[1] 付阿丹[2] 丁婷[1] 朱江[2] 

机构地区：[1]湖北省武汉市中心医院血液科,430014 [2]湖北省武汉市中心医院护理部,430014

出　　处：《中华现代护理杂志》2016年第2期272-274,共3页Chinese Journal of Modern Nursing

摘　　要：目的 探讨浓盐水加甲硝唑坐浴对急性白血病合并肛周感染的治疗效果.方法 选择2010年6月—2014年12月急性白血病合并肛周感染的76例患者,将其按入院时间分为对照组38例和观察组38例;两组均给予急性白血病常规护理,针对不同菌种,应用敏感抗生素进行全身治疗的同时,对照组常规用1：5000高锰酸钾坐浴,观察组用1.6%浓盐水加0.1%甲硝唑溶液坐浴.于30 d后比较两组患者治疗肛周感染的恢复效果.结果 在76例患者中,观察组治疗有效率为94.7%,高于对照组（78.9%）,治疗后观察组患者肛周病原菌培养结果优于对照组,差异均有统计学意义（χ2值分别为4.15,12.48;P〈0.05）.结论 对急性白血病合并肛周感染患者采用浓盐水联合甲硝唑坐浴是一种行之有效、便捷的治疗方法,值得在临床上推广使用.Objective To explore the effects of high-concentrated brine with metronidazole sitz bath on the treatment of perianal inflammation in leukemia patients. Methods The study investigated 76 acute leukemia patients with perianal inflammation who were hospitalized from June 2010 to December 2014. The participants were randomly divided into two groups：control group and observation group, 38 cases in each group. Based on the normal nursing care and antibiotic therapy, the patients of control group received 1 ： 5000 potassium permanganate sitz bath; the patients of observation group received 1. 6% high-concentrated brine with 0. 1%metronidazole sitz bath. The recovery effects of patients′perianal inflammation would be compared after 30 days. Results Treatment effective rate of the observation group （94. 7%） was higher than that of the control group （78. 9%）;the positive rate of perianal pathogenic bacteria of the observation group was lower than that in the control group （χ2 =4. 15, 12. 48; P 〈0. 05）. Conclusions The method of high-concentrated brine with metronidazole sitz bath is effective and convenient on the treatment of perianal inflammation in leukemia patients, and it should be further developed in clinical practice.

关 键 词：急性白血病 肛周感染 盐水 甲硝唑 坐浴 

分 类 号：R473.73[医药卫生—护理学]