子宫输卵管超声造影卵巢周边环状增强与自然妊娠结局的相关性研究  

Correlation Between Ovarian Surrounding Circular Enhancement of Hysterosalpingo- contrast Sonography and Natural Pregnancy Outcomes

作　　者：江岚[1] 谢亦农[1] 梁伟翔[1] 王伟群[1] 

机构地区：[1]广州医科大学附属第三医院超声医学科,广东省广州市510150

出　　处：《中国全科医学》2016年第20期2410-2415,共6页Chinese General Practice

基　　金：广州医科大学青年科研项目(2012A12)

摘　　要：目的通过分析子宫输卵管超声造影卵巢周边环状增强与自然妊娠结局的相关性,探讨卵巢周边环状增强在评价输卵管功能方面的临床应用价值。方法选取2013年1月—2014年12月在广州医科大学附属第三医院生殖助孕中心及妇科不孕门诊就诊的患者139例。采用六氟化硫微泡（Sono Vue）造影剂进行子宫输卵管超声造影术（HyCoSy）,观察输卵管末端造影剂在卵巢周边增强的超声特征,根据造影剂是否在卵巢周边形成环状增强,分为双侧输卵管超声造影环状增强组、双侧输卵管超声造影无环状增强组及单侧输卵管超声造影环状增强组;并进一步将环状增强分为0、1、2、3级。对患者进行随访,分析子宫输卵管超声造影卵巢周边环状增强与自然妊娠结局的相关性。结果139例患者包括268条输卵管,单侧输卵管10条（10例）,双侧输卵管258条（129例）;左侧输卵管133条（133例）,右侧输卵管135条（135例）;54例患者自然妊娠成功,85例患者自然妊娠失败。排除单侧输卵管患者,双侧输卵管超声造影环状增强组57例,自然妊娠成功41例（71.9%）;双侧输卵管超声造影无环状增强组49例,自然妊娠成功7例（14.3%）;单侧输卵管超声造影环状增强组23例,自然妊娠成功4例（17.4%）。不同输卵管超声造影环状增强组自然妊娠成功率比较,差异有统计学意义（χ~2=42.499,P〈0.001）。左侧输卵管超声造影环状增强0级22例,自然妊娠成功2例（9.1%）;1级40例,自然妊娠成功5例（12.5%）;2级42例,自然妊娠成功21例（50.0%）;3级29例,自然妊娠成功24例（82.8%）。右侧输卵管超声造影环状增强0级28例,自然妊娠成功6例（21.4%）;1级41例,自然妊娠成功5例（12.2%）;2级35例,自然妊娠成功16例（45.7%）;3级31例,自然妊娠成功27例（87.1%）。左、右侧输卵管超声造影不同环状增强分级者自然妊娠成功率比较,差异有统计学意义（χObjective To analyse the correlation between ovarian surrounding circular enhancement of hysterosalpingo- contrast sonography（ HyCoSy） and natural pregnancy outcomes, and investigate the clinical value of ovarian surrounding circular enhancement in the evaluation of the function of fallopian tube. Methods From January 2013 to December 2014,we enrolled 139 patients who received treatment in the Reproductive Assisted Reproduction Center and the outpatient Department of Gynecology and Infertility of the Third Affiliated Hospital of Guangzhou Medical University. Hy Co Sy was conducted using Sono Vue contrast agent,and the ultrasonography features of contrast agent at the end of the fallopian tube were observed. According to whether or not contrast agent form circular enhancement sorrounding ovary,the patients were divided into the group of bilateral fallopian tube ultrasound contrast circular enhancement,the group of bilateral fallopian tube without ultrasound contrast circular enhancement,and the group of unilateral fallopian tube with ultrasound contrast circular enhancement,and circular enhancement was further divided into grade 0,1,2 and 3. Follow- up was conducted on the patients, and the correlation between the ultrasonography features of ovarian surrounding circular enhancement and natural pregnancy outcomes was analyzed. Results268 fallopian tubes were involved in the 139 patients, including 10 unilateral fallopian tubes（ 10 patients）,258 bilateral fallopian tubes（ 129 patients）,133 left fallopian tubes（ 133 patients）, and 135 right fallopian tubes（ 135 patient）. 54 patients had successful pregnancy,and 85 patients had failed natural pregnancy. After the exclusion of patients with unilateral fallopian tube,there were 57 patients in the group of bilateral fallopian tube ultrasound contrast circular enhancement,among which 41（ 71. 9%） patients had successful natural pregnancy; there were 49 patients in the group of bilateral fallopian tube without ultrasound contrast circular enhancement

关 键 词：子宫输卵管造影术 妊娠 不育 女(雌)性 

分 类 号：R816.91[医药卫生—放射医学] R711.6[医药卫生—临床医学]