儿童青少年注意问题与焦虑/抑郁的双生子研究  

A twin study on attention problems and anxiety/depression in children and adolescents

作　　者：王上上[1] 陈天娇[1] 季成叶[1] 

机构地区：[1]北京大学公共卫生学院/儿童青少年卫生研究所,北京100191

出　　处：《中国学校卫生》2016年第7期995-997,共3页Chinese Journal of School Health

摘　　要：目的了解儿童青少年双生子注意问题和焦虑/抑郁的遗传度,为探讨遗传和环境因素对儿童青少年注意问题和焦虑/抑郁的影响程度提供依据。方法采用Achenbach儿童行为量表（CBCL）家长用问卷,对从北京地区和山东地区招募的527对同性别6～18岁双生子进行调查,采用相关系数法计算注意问题和焦虑/抑郁的遗传度。结果不同卵性双生子中男、女比例差异无统计学意义（χ^2=0.083,P〉0.05）。注意问题和焦虑/抑郁得分在同卵双生子和异卵双生子间差异均无统计学意义（t值分别为0.024,-0.593,P值均〉0.05）。儿童青少年注意问题遗传度为0.78,焦虑/抑郁遗传度为0.52。结论遗传对儿童青少年注意问题有高等强度影响,遗传和环境因素共同作用于儿童青少年焦虑与抑郁。Objective To estimate the heritability of attention problems and anxiety/depression in children and adolescents. Methods A total of 527 same-sex twin pairs aged 6-18 years participated in this study. Attention problems and anxiety / depression problems were assessed with the Child Behavior Checklist（ CBCL）. Intraclass correlation coefficient method was performed to investigate the heritability of attention problems and anxiety / depression problems of children and adolescents. Results The heritability of attention problems and anxiety / depression problems in children and adolescents are 0.78 and 0.52, respectively. Conclusion Attention problems in children and adolescents are mainly determined by the genetic factors. Both of genetic and environmental factors may play roles in anxiety / depression problems of children and adolescents.

关 键 词：注意力缺陷障碍伴多动 焦虑 抑郁 双生子研究 儿童 

分 类 号：R395.6[哲学宗教—心理学] R749.72[医药卫生—医学心理学]