血浆骨桥蛋白水平与冠状动脉病变相关性研究  

Research of correlation between plasma osteopontin level and coronary artery disease

作　　者：刘艳宾[1] 金卫东[1] 秦洁洁[1] 邢永生[1] 

机构地区：[1]河南省新乡市中心医院心内一科,453000

出　　处：《中国现代药物应用》2016年第13期35-36,共2页Chinese Journal of Modern Drug Application

摘　　要：目的探讨血浆骨桥蛋白水平与冠状动脉病变支数的相关性。方法选取100例经冠状动脉造影术证实的冠心病患者(冠心病组),另取50例非冠心病患者(非冠心病组),比较其血浆骨桥蛋白水平。结果冠心病组血浆骨桥蛋白水平明显高于非冠心病组(P<0.05);冠心病不同冠脉病变支数患者血浆骨桥蛋白水平比较差异有统计学意义(P<0.05)。结论冠心病患者血浆骨桥蛋白水平明显升高,且与冠状动脉病变相关。Objective To investigate correlation between plasma osteopontin level and number of coronary artery disease. Methods There were 100 patients with confirmed coronary heart disease by coronary angiography （coronary heart disease group） and 50 patients without coronary heart disease （non-coronary heart disease group）. Their plasma osteopontin levels were compared. Results The coronary heart disease group had obviously higher plasma osteopontin level than the non-coronary heart disease group （P〈0.05）. The difference of plasma osteopontin levels in patients with different number of coronary artery disease had statistical significance （P〈0.05）. Conclusion Remarkably increased plasma osteopontin level in coronary heart disease patients is correlated with coronary artery disease.

关 键 词：冠心病 骨桥蛋白 

分 类 号：R541.4[医药卫生—心血管疾病]