耐多药肺结核中医证候与肺部影像相关性研究  

A study on the correlation between TCM syndromes of multidrug-resistant tuberculosis and lung image

作　　者：黄颖新 孟庆龙[2] 陈曦 张智勇 相尧 

机构地区：[1]长春市传染病医院,吉林长春130123 [2]长春市南关区中医院,吉林长春130000

出　　处：《中医临床研究》2016年第13期8-11,共4页Clinical Journal Of Chinese Medicine

摘　　要：目的:通过分析耐多药肺结核中医证候一般分布特征、中医证候与肺部病变范围和空洞情况相关性,初步明确耐多药肺结核中医证候分布规律。方法:采用临床流行病学方法研究120例耐多药肺结核患者的证候分布及与影像学的关系,具体为设计统计分类表,标注证候、性别、年龄、病程、肺部病变范围、空洞情况、耐药基因突变位点等条目,建立Excel数据库,提取中医证候分布信息,确定数量、出现频率等,进行统计学比较。结果:120例耐多药肺结核患者中医证候分布排序依次为阴虚火旺证(40.83%)、气阴两虚证(38.33%)、阴阳两虚证(11.67%)、肺阴亏虚证(9.17%)。肺阴亏虚证与阴虚火旺证、气阴两虚证比较,其肺部病变范围相对较小;阴虚火旺证、气阴两虚证、阴阳两虚证三型肺部病变范围无明显差异。阴虚火旺证出现肺部空洞的表现与肺阴亏虚证、气阴两虚证、阴阳两虚证比较相对较多;肺阴亏虚证、气阴两虚证、阴阳两虚证三型出现肺部空洞表现的情况无明显差异。结论:耐多药肺结核中医证候分布排序为阴虚火旺证、气阴两虚证、阴阳两虚证、肺阴亏虚证。肺阴亏虚证与阴虚火旺证、气阴两虚证、阴阳两虚证等比较,肺部病变范围较轻。阴虚火旺证与肺阴亏虚证、气阴两虚证、阴阳两虚证等比较,肺部空洞病变最为严重。Objective： To explore the general distribution characteristic, correlation between TCM syndromes with extent of lung disease and hole situations, initially identify the TCM syndromes distribution rules for multi-drug resistant tuberculosis- Methods： Through clinical epidemiology methods, correlation distribution between TCM syndromes and imaging of 120 patients with multi-drug resistant tuberculosis was studied- It included designing statistical classification tables, labeling syndromes, gender, age, course of disease, lung disease, the range of hole, and the resistance gene mutation sites of entry- Excel databases were established- Distribution of TCM syndromes was extracted- The number and frequency were observed for statistical comparison- Results： 120 patients＇ s TCM syndrome distribution sort followed by the Yinxu Huowang syndrome（40-83%）, the Qiyin Liangxu syndrome（38-33%）, the Yinyang Liangxu syndrome（11-67%）, the Feiyin Kuixu syndrome（9-17%）- Compared with the Yinxu Huowang syndrome and the Qiyin Liangxu syndrome, the range of lung lesions of the Feiyin Kuixu syndrome was smaller, but the difference among three groups were not significantly statistical- Compared with the Feiyin Kuixu syndrome, the numbers of holes in lung of the Qiyin Liangxu syndrome and the Yinyang Liangxu syndrome were increased, but the difference among three groups were not significantly statistical- Conclusion： The order of MDR-TB syndromes distribution was the Yinxu Huowang syndrome, the Qiyin Liangxu syndrome, the Yinyang Liangxu syndrome and the Feiyin Kuixu syndrome- Compared with other syndromes, the range of lung lesions of the Feiyin Kuixu syndrome were smaller; the numbers of holes in lung of the Yinxu Huowang syndrome were increased.

关 键 词：耐多药肺结核 证候 影像学 

分 类 号：R521[医药卫生—内科学]