尤特奇在纳米制剂中的应用进展  

Application progress of eudragit nanoparticles

作　　者：王洁敏[1] 王雄飞[1] 王娇[1] 王静[1] 曹德英[1] 

机构地区：[1]河北医科大学药学院药剂教研室,石家庄050017

出　　处：《中国新药杂志》2016年第14期1613-1616,共4页Chinese Journal of New Drugs

摘　　要：综述尤特奇在纳米制剂中的应用进展,为研究者了解和使用尤特奇制备纳米制剂提供信息。通过查阅中外文献,对尤特奇系列辅料在纳米制剂中的应用进行归纳与总结。尤特奇纳米制剂可以通过控制药物释放速率、提高药物溶解度和稳定性来提高其生物利用度和疗效;且尤特奇能与其他材料混合制备纳米制剂;并能辅助中空纳米粒子的制备。尤特奇在纳米制剂中的应用具有广阔的前景。To review the application progress of eudragit in nano-preparations,providing information of understanding and using eudragit to prepare nanopaticles. Through reviewing of domestic and foreign literature,the application of eudragit series materials in nano-preparations was summarized. Eudragit nanopaticles can improve drug bioavailability and efficacy by controlling the release rate of drug,and enhancing the solubility and stability of drugs. Moreover,eudragit can be used for preparing nano-formulation with other materials,and is helpful to prepare hollow nanoparticles. Eudragit has broad application prospects in preparing nanopaticles.

关 键 词：尤特奇 纳米制剂 生物利用度 中空纳米粒子 

分 类 号：R94[医药卫生—药剂学]