X线放射吸收法指骨骨密度测定在绝经后女性骨质疏松症诊断中的应用  

Application of Identifying postmenopausal women with osteoporosis by dual energy X-ray absorptiometry and phalangeal radiographic absorptiometry

作　　者：韦丽娅[1] 王培[1] 甘小玲[1] 余佳莹[1] 陈庆瑜[1] 

机构地区：[1]中山大学孙逸仙纪念医院体检中心,广东广州510120

出　　处：《吉林医学》2016年第8期1922-1924,共3页Jilin Medical Journal

摘　　要：目的:评价X线放射吸收法(Radiographic Absorptiometry,RA)测定指骨骨密度与双能X线吸收法(Dual energy X-ray radiogrammetry,DEXA)测定腰椎和股骨颈骨密度在诊断绝经后女性骨质疏松症的一致性。方法:选取65名绝经后女性,均用RA测定指骨骨密度和DEXA测定腰椎和股骨颈骨密度,用线性回归分析比较两种方法所测的骨质量(Bone mineral density,BMD),用Bland-Altman(B-A)作图法分析比较两种方法所测T值。结果:RA测定指骨BMD与DEXA测定腰椎和股骨颈BMD呈线性关系,相关系数R2分别为0.64、0.56(P<0.01)。B-A分析法显示两种方法检测T值的一致性较好。结论:RA指骨骨密度测定法可应用于绝经后女性骨质疏松症的筛查。Objective To compare the ability of phalangeal radiographic absorptiometry（RA）to identify osteoporosis with dual energy X -ray absorptiometry （DEXA） in postmenopausal women.Method A total of 65 postmenopausal women were en-rolled.Bone mineral density （BMD）of phalange was measured using RA and central sites （lumbar vertebra and neck of femur）u-sing DEXA.The concordance of BMD between phalanges and central sites was measured by linear -regression analysis.And T -scores between phalanges and central sites were measured by Bland -Altman analysis.Results The mean BMD of phalange had a linear relationship with that of lumbar vertebra and neck of femur.The correlation coefficient R2 was 0.64,0.56,respectively （P 〈0.01）.B -A analysis showed T -score of phalange measured using RA and T -score of lumbar vertebra and neck of femur meas-ured using DEXA were in good agreement.Conclusion Phalangeal radiographic absorptiometry is an effective way to identify osteo-porosis in postmenopausal women.

关 键 词：骨密度 骨质疏松症 指骨 X光放射吸收法 腰椎 股骨颈 双能X线 

分 类 号：R580[医药卫生—内分泌] R816.8[医药卫生—内科学]