病毒性心肌炎病原学检测研究进展  

Pathogen detection for viral myocarditis

作　　者：李景业[1] 马长生[1] 

机构地区：[1]首都医科大学附属北京安贞医院心血管内科国家心血管病临床医学研究中心,北京100029

出　　处：《临床心血管病杂志》2016年第7期658-662,共5页Journal of Clinical Cardiology

基　　金：科技部国际科技合作基金项目(No:2013DFB30310);北京市医院管理局临床医学发展专项经费资助(No:ZYLX201302);"十二五"国家科技支撑计划基金项目(No:2013BAI09B02)

摘　　要：病毒性心肌炎为嗜心肌病毒感染所致心肌炎性病变,早期临床表现缺乏特异性,确诊需依靠病原学检查。心肌组织中各类病毒的检出率受取材部位、固定方法、标本数量等多种因素影响。对常用病原学检测方法、嗜心肌病毒检出率及其影响因素的认识,有助于判断疾病进程,指导临床治疗。Myocarditis is an inflammatory disease of the myocardium caused by cardiotropic viral infection.Considering the highly variable clinical manifestation,pathogen detection is needed to substantiate the diagnosis of early-stage viral myocarditis.Prevalence of cardiotropic viruses in endmyocardial biopsies depends on site of sampling,method of tissue fixation and the number of myocardial samples.A better understanding of the common approaches of pathogen detection,as well as the prevalence of cardiotropic virus and its influential factors is of major interest for assessing the treatment strategies and time course of the disease.

关 键 词：病毒性心肌炎 病原学检测 检出率 

分 类 号：R542.2[医药卫生—心血管疾病]