芦荟凝胶对烧烫伤创面的促愈作用  

Promoting Healing Effects on Accreting Raw Surface in Burning and Scald of Skin with Aloe Gel

作　　者：刘川玉[1] 唐建红[1] 邵家松[1] 何洁[1] 蔡海燕[1] 周美芳[1] 

机构地区：[1]桂林医学院附属医院,广西桂林541001

出　　处：《中国现代应用药学》2016年第7期931-933,共3页Chinese Journal of Modern Applied Pharmacy

基　　金：广西科学研究与技术开发计划项目(桂科攻1355004-8);桂林市科学研究与技术开发计划项目(20110322);广西教育厅科技项目(2013LX073);广西卫生厅科技计划课题(Z2011166);广西卫生厅中医药科技专项课题(GZYZ1129)

摘　　要：目的观察芦荟凝胶对烧烫伤创面愈合及瘢痕形成的影响。方法将100例烧烫伤患者,其中男性55例,女性45例,年龄15-65岁,平均为（37.5±3.2）岁,随机分为对照组和治疗组各50例,采用相同的方法清创处理,暴露或包扎治疗,治疗组用湿润烧伤膏加芦荟凝胶治疗,对照组用湿润烧伤膏治疗,将药物均匀涂抹在创面,厚度约为1 mm,每天3次,观察2组患者创面愈合时间、感染率、瘢痕形成、色素沉着及不良反应等情况。结果治疗组和对照组的平均创面愈合时间分别为（10.2±1.1）d和（16.7±1.9）d,感染率分别为4%和16%,瘢痕形成率分别为4%和22%,治愈率分别为96%和72%,色素沉着数分别为9和23,2组患者都没有出现明显的不良反应现象,2组观察指标比较差异均有统计学意义（P〈0.05）。结论芦荟凝胶对烧烫伤创面具有明显的促愈作用,并能减少瘢痕的形成。OBJECTIVE To observe the effect on accreting raw surface and scarring in burning and scald of skin with aloe gel. METHODS There were 100 patients suffered burning and scald of skin, and there were 55 male patients and 45 female patients, they were 15-65 years old that averagely 37.5？3.2 years old. Patients were randomly divided into control group and treatment group, 50 patients in each group. The two groups received treatment of debriding, exposing or wrapping. The treatment group were treated with the burning and scald paste in moistening and aloe gel, and the control group were treated only with the burning and scald paste in moistening. The above drugs were coated well-distributedly onto the wound surfaces with the depth of about 1 mm in 3 times per day. Then the clinical informations of two groups of patients＇ wound healing time, the rate of infection, the formation of scar, the occurring of pigmentation and the adverse reactions were observed. RESULTS The average curing time in treatment and contro group was（10.2±1.1）d and（16.7±1.9）d, respectively, the rate of infection in two groups was 4% and 16%, the scarring rate was 4% and 22%, and the cure rate was 96% and 72%, the occurring of pigmentation was 9 and 23. The two groups of patients hadn＇t presented the obvious adverse reactions. The comparation of difference on the observation of outcomes in the two groups had statistical significance（P〈0.05）. CONCLUSION Aloe has obvious effect on accreting raw surface and scarring in burning and scald of skin as well as reducing the formation of scar.

关 键 词：芦荟凝胶 烧伤 烫伤 创面 促愈作用 

分 类 号：R969.4[医药卫生—药理学]