超声与MRI对胎儿神经系统发育异常的诊断分析  

The diagnosis and prognosis of the fetal nervous system abnormalities by the ultrasound combined with MRI

作　　者：张旭辉[1] 陈晓荣[1] 张珊珊[1] 

机构地区：[1]湖北医药学院附属东风医院影像科,十堰442008

出　　处：《磁共振成像》2016年第7期487-490,共4页Chinese Journal of Magnetic Resonance Imaging

基　　金：十堰市科学技术研究项目(编号:14Y52)

摘　　要：目的探讨超声与MRI对胎儿神经系统发育异常的诊断价值,并分析相关预后情况。材料与方法对28例超声提示胎儿中枢神经系统异常或可疑异常的孕妇进行超声与MRI检查,对预后情况进行分析。结果超声提示后颅窝异常20例,其中小脑延髓池增宽16例,Dandy-walker畸形2例、小脑发育不良2例;颅内囊性占位4例,小头畸形3例,透明隔腔异常1例。MRI提示胎儿神经系统正常4例,MRI提示后颅窝异常19例,其中小脑延髓池增宽15例,Dandy-walker畸形2例、小脑发育不良2例;颅内囊性占位3例,小头畸形2例。通过调查与随访对比,超声诊断的符合率为78.6%,MRI诊断的符合率为100.0%,MRI诊断的符合率明显高于超声诊断(P<0.05)。28例胎儿出生正常19例,引产7例,胎死2例。结论相对于超声,MRI对胎儿神经系统发育异常有更好的诊断符合率,有利于进行预后判断,两者联合使用是临床医生确定诊疗方案的重要依据。Objective： To investigate the diagnosis values of the fetal nervous system abnormalities by the ultrasound combined with MRI and analysis the relevant prognosis. Materials and Methods： From february 2011 to january 2015, selected 28 cases of fetal central nervous system abnormalities ultrasonic tips or suspicious abnormalities in pregnant women in our hospital, all the pregnant women were given the both ultrasound and MRI for diagnosis and to investigate the situation on the prognosis. Results： By the ultrasound diagnosis, there were 20 cases of tips fossa abnormalities（which 16 cases with cisterna widened, 2 cases with Dandy-walker malformation, 2 cases with cerebellar hypoplasia）. Four case with cystic intracranial space-occupying four cases, 3 cases with microcephaly, 1 case with septum cavity abnormal. By the MRI diagnosis, there were 4 cases with normal fetal nervous system, 19 cases of tips fossa abnormalities（which 15 cases with cisterna widened, 2 cases with Dandy-walker malformation, 2 cases with cerebellar hypoplasia）. Three case with cystic intracranial space-occupying four cases, 2 cases with microcephaly. Through investigation and followed-up contrast, The ultrasound diagnosis consistent rates was 78.6%, so that were 100.0% by the MRI diagnosis that compared were significantly difference（P〈0.05）. Twenty-eight cases of 19 cases of normal birth, 7 cases were abortion, 2 cases of fetal death. Conclusion： Relative to the ultrasound, MRI of the fetal nervous system abnormalities has better consistent rates of diagnosis, prognosis is conducive to both joint use is important basis for the clinician to determine the treatment program.

关 键 词：超声 核磁共振 胎儿神经系统发育异常 预后 

分 类 号：R445.2[医药卫生—影像医学与核医学] R714.431[医药卫生—诊断学]