北京市西城区2011—2014年麻疹疑似病例血清学检测  

Serological detection of suspected measles cases in Xicheng District of Beijing,2011-2014

作　　者：张晶波[1] 崔京辉[1] 李达[1] 王敬辉[1] 王永全[1] 

机构地区：[1]北京市西城区疾病预防控制中心,北京100120

出　　处：《中国感染控制杂志》2016年第7期501-503,共3页Chinese Journal of Infection Control

摘　　要：目的了解北京市西城区麻疹疑似病例的血清学检测情况,为麻疹的监测与预防提供依据。方法分析2011—2014年北京市西城区麻疹疑似病例200份血标本的检测结果及年龄分布情况。结果 2011—2014年麻疹疑似病例血清学检测阳性率为32.50%(65/200);各年份血清学检测阳性率分别为12.00%、4.35%、33.90%和44.09%;不同年份血清学检测阳性率比较,差异有统计学意义(P<0.001)。200例麻疹疑似病例中,<5岁组65例,血清学检测阳性率为35.38%;>24岁组97例,血清学检测阳性率为34.02%;31例接种疫苗,接种率为15.50%;IgM抗体阳性病例疫苗接种率(3.08%)低于IgM抗体阴性病例(21.48%),差异有统计学意义(P<0.001)。结论 2011—2014年北京市西城区麻疹血清检测阳性率2012年降低,然后逐年上升,5岁以下儿童通过麻疹疫苗免疫接种麻疹将得到控制,为实现消除麻疹的计划,有效控制和预防成人麻疹发病具有重要意义。Objective To understand the serological detection of suspected measles cases in Xicheng District of Beijing,and provide basis for monitoring and prevention of measles.Methods Detection results of 200 blood speci-mens and age distribution of suspected measles cases in Xicheng District of Beijing in 2011 -2014 were analyzed. Results The positive rate of serological detection of suspected measles cases in 2011-2014 was 32.50%（65/200）;positive rates in each year were 12.00%,4.35%,33.90%,and 44.09% respectively;there was significant differ-ence in the positive rate of serological tests in different years（P 〈0.001）.Of 200 cases,65 were 〈5 years old,and 97 were 〉24 years old,positive rates of serological detection were 35.38% and 34.02% respectively;31 cases （15.50%）received vaccination of measles;vaccine coverage rate in IgM antibody positive cases was lower than IgM antibody negative cases （3.08% vs 21 .48%,P 〈0.001 ）.Conclusion Positive rate of serological detection de-creased in 2012,then increased year by year,for children under 5 years,measles are controlled by immunization with measles vaccine,in order to achieve the goal of eliminating measles effectively,control and prevention of adult measles is of great significance.

关 键 词：麻疹 IGM 抗体 疑似病例 血清学检测 

分 类 号：R511.1[医药卫生—内科学]