量表EORTC QLQ-OES18在中国食管癌患者中的有效性验证  

Validation of EORTC QLQ-OES18 scale in Chinese patients with esophageal cancer

作　　者：李惠霞[1] 杨华[1] 郎文静[1] 林允寿 张雷[1] 曹娜[1] 韩冬[1] 

机构地区：[1]天津医科大学肿瘤医院/国家肿瘤临床医学研究中心/天津市肿瘤防治重点实验室食管肿瘤科,天津300060

出　　处：《重庆医学》2016年第21期2969-2972,共4页Chongqing medicine

摘　　要：目的验证欧洲癌症研究与治疗组织（EORTC）食管癌患者补充量表（QLQ-OES18）在中国食管癌患者中的有效性。方法采用EORTC QLQ-OES18问卷对112例食管癌患者进行生活质量测定,对各条目结果采用克朗巴哈系数、Spearman相关分析、多项加强分析和Wilcoxon Rank Sum检验进行统计分析。结果吞咽困难、进食、反流和疼痛4个多条目维度的克朗巴哈α系数为0.607-0.822,且所有条目与自身维度的相关系数均大于其他维度的相关系数。QLQ-OES18各维度与癌症患者生活质量核心量表标准问卷（QLQ-C30）各维度的相关性系数的绝对值为0.002-0.538。在不同的卡氏功能状态量表（KPS）分组中,仅吞咽口水条目组间比较,差异有统计学意义（P〈0.05）。结论 EORTC QLQ-OES18具有良好的信度和效度,可运用于临床评估食管癌患者的生活质量。Objective To validate the effectiveness of the Chinese version of the EORTC QLQ-OES18 in the patients with esophageal cancer.Methods The QLQ-OES18 questionnaire was used to assess the quality of life in 112 patients with esophageal cancer.The results of various items were statistically analyzed by adopting the Cronbach′s coefficient,Spearman correlation analysis,multiple strengthen analysis and Wilcoxon Rank Sum test.Results The Cronbach′sαcoefficient of four multi-item dimensions（dysphagia,eating,reflux and pain）was 0.607-0.822,moreover the correlation coefficients of all items with their own dimensions were more than those of other dimensions.The absolute values of correlation coefficients in each dimension between EORTC QLQOES18 and EORTC QLQ-C30 were 0.002-0.538.The difference of swallowing item among the groups by KPS scores had statistical significance（P〈0.05）.Conclusion EORTC QLQ-OES18 scale has better credibility and validity,and can be used for evaluating the quality of life in the patients with esophageal cancer.

关 键 词：食管癌 生活质量 食管癌患者生活质量专用量表 有效性验证 

分 类 号：R735.1[医药卫生—肿瘤]