2006-2015年东莞市无偿献血者丙肝病毒感染情况分析  

Analysis of HCV infection among voluntary blood donors in Dongguan city from 2006 to 2015

作　　者：钟炽辉[1] 张玉曌 黄志森[1] 何子毅[3] 曾涛[2] 

机构地区：[1]东莞市中心血站献血服务科,广东东莞523930 [2]南方医科大学南方医院检验医学科,广东广州510515 [3]东莞市中心血站检验科,广东东莞523930

出　　处：《分子诊断与治疗杂志》2016年第4期261-264,共4页Journal of Molecular Diagnostics and Therapy

基　　金：东莞市科技计划项目(20131051010021)

摘　　要：目的了解本地区无偿献血人群丙肝病毒感染现状和流行趋势,为献血相关政策制定提供科学依据。方法利用酶联免疫吸附法对本血站2006年1月至2015年12月共计703 427例无偿献血者的血标本进行抗-HCV检测。结果本地区献血人群近10年抗-HCV总阳性率为0.31%,整体呈逐年下降趋势;女性献血者抗-HCV阳性率低于男性(P<0.05);抗-HCV阳性率随献血者的文化程度升高而大致呈下降趋势(P<0.05)。多次献血者抗-HCV阳性率明显低于初次献血者(P<0.05)。结论女性、高文化程度、重复献血人群的HCV感染率较低,应作为东莞地区无偿献血的招募重点对象。Objective To provide scientific base for the relevant policies of voluntary blood donation by investigating the status and trends of hepatitis C virus（HCV） infection in local voluntary blood donors. Method Anti-HCV antibody in 703 427 cases of specimens obtained from the blood donors were detected by using enzyme linked immunosorbent assay（ELISA） from January 2006 to December 2015.Results The total positive rate of anti-HCV in local blood donors was 0.31% among the most recent 10 years, which showed a declining trend year over year. Women were found to have a lower positive rate than men（P〈0.05）. The positive rate was also negatively correlated with the growth of cultural degrees in blood donors. Moreover, the positive rate was significantly lower among repeated donors compared to first time donors（P〈0.001）. Conclusion Female, better educated, and repeated donors should be regarded as the better objects for the recruitment voluntary blood donors in Dongguan city, because of the lower positive rate in HCV infection.

关 键 词：丙肝病毒 献血者 丙肝抗体 血液安全 东莞 

分 类 号：R512.63[医药卫生—内科学] R446.6[医药卫生—临床医学]