小儿推拿配合定痫丸治疗特发性癫痫患儿机理研究  

Mechanism of Treatment on the Children with Idiopathic Epilepsy by Infantile Massage and Taking Dingxian Pills

作　　者：张献[1] 李崖雪[2] 刘潇[2] 邵音 孙士红[2] 宣威[2] 

机构地区：[1]黑龙江中医药大学,黑龙江哈尔滨150040 [2]黑龙江中医药大学附属第一医院,黑龙江哈尔滨150040

出　　处：《中医药信息》2016年第4期90-92,共3页Information on Traditional Chinese Medicine

基　　金：黑龙江省中医药管理局科研项目(No.ZHY12-Z044)

摘　　要：目的:探讨小儿推拿手法配合定痫丸治疗小儿特发性癫痫(全面强直—阵挛发作)的机制。方法:将符合纳入标准的60例患儿采用奇偶法随机分为3组,每组20例。应用双抗体夹心ELISA法检测血清IL-1β、IGF-1含量变化。结果:推拿配合药物组可明显减少血清中白细胞介素-1β(IL-1β)含量、增加胰岛素样生长因子-1(IGF-1)含量,与推拿组、药物组比较,差异具有统计学意义(P<0.05)。结论:推拿配合定痫丸治疗特发性癫痫临床效果较好,其作用机制可能与降低IL-1β水平,升高IGF-1水平相关。Objective：To observe the mechanism of treatment on children with idiopathic epilepsy by infantile massage and taking Dingxian pills. Methods： We randomly deride 60 eases with idiopathic epilepsy into three groups ,20 cases in each group. Record the levels of IL - 1β and IGF - 1 in the serum of children with epilep. sy . Results： The infantile massage and taking Dingxian pills could significantly reduce the levels of IL - 1β and increase the levels of IGF - 1 in the serum of children with epilepsy compared with other two groups （ P 〈 0.05 ）. Conclusion ： The paper reveals the mechanism of treatment on children with idiopathic epilepsy by in- fantile massage and taking Dingxian pills.

关 键 词：小儿推拿配合药物 特发性癫痫 白细胞介素1 胰岛素样生长因子 

分 类 号：R244.1[医药卫生—针灸推拿学]