应用三维斑点追踪成像技术对扩张型心肌病患者心肌运动变化特点的研究  

Changing Characteristics of Myocardial Movement in Patients with Dilated Cardiomyopathy Identified by Three-dimensional Speckle Tracking Echocardiography

作　　者：刘慧[1] 李颖[1] 任卫东[1] 刘开薇 宋光[1] 毕文静[1] 赵一婷[1] 

机构地区：[1]中国医科大学附属盛京医院超声科,沈阳110004

出　　处：《中国医科大学学报》2016年第8期704-707,共4页Journal of China Medical University

基　　金：辽宁省科学技术计划(2013225049)

摘　　要：目的应用三维斑点追踪成像（3D-STE）技术研究扩张型心肌病（DCM）患者心肌运动变化的特点。方法应用3D-STE技术分析69例DCM患者左心室收缩期总体纵向应变（GLS）、径向应变（GRS）、圆周应变（GCS）以及面积应变（GAS）峰值。按照左心室射血分数（LVEF）将所有患者分为A组（LVEF：35%~50%）和B组（LVEF：〈35%）,比较2组各测量值差异,并分析各总体应变与LVEF的相关性。结果 A组GLS、GRS、GCS、GAS均高于B组（P〈0.01）。A组GLS、GRS、GCS、GAS与LVEF均具有相关性（r分别为-0.871、0.610、-0.423、-0.797,P〈0.05）;B组GCS、GRS、GAS与LVEF具有相关性（r分别为-0.517、0.368、-0.438,P〈0.05）,GLS与LVEF无明显相关性。结论 3D-STE技术可以评价DCM患者心肌运动变化,GLS可以作为DCM患者预后的重要参考指标。Objective To investigate the changing characteristics of myocardial movement in patients with dilated cardiomyopathy by three-dimensional speckle tracking echocardiography（3D-STE）. Methods The peak systolic global longitudinal train（GLS）,global radial strain（GRS）,global circumferential stain（GCS）and global area strain（GAS）of left ventricle were measured by 3D-STE technology in 69 patients with dilated cardiomyopathy. According to the left ventricular ejection fraction（LVEF）,all patients were divided into group A（35%≤LVEF〈50%）and group B（LVEF〈35%）. The differences of measurements were compared between two groups. The correlation between global myocardial strain in all directions and left ventricular ejection fraction was analyzed. Results The GLS,GRS,GCS and GAS were significantly higher in group A than those in group B（P〈0.01）. The GLS,GRS,GCS and GAS were correlated with LVEF in group A（r =-0.871,0.610,-0.423,-0.797;P〈0.05）.The GCS,GRS and GAS were correlated with LVEF in group B（r =-0.517,0.368,-0.438;P〈0.05）. There was no significant correlation between GLS and LVEF in group B. Conclusion 3D-STE technology can be applied to evaluate the change of the myocardial movement. GLS is a promising marker of the prognosis in patients with DCM.

关 键 词：超声心动图 三维 应变 斑点追踪技术 心肌病 扩张型 

分 类 号：R445.1[医药卫生—影像医学与核医学]