一种水溶性探针的合成及对双氧水的比色荧光检测  

Synthesis of a water solution probe and fluorescence and colorimetric sensor for detection of H_2O_2

作　　者：邓燕[1] 文思雨 皮毅兵 蒋倩婷[1] 梁敏[1] 刘亮亮[1] 郭雨芳 严奉梅 张春香[1] 申有名[1] 郑清云[1] 张向阳[1] 

机构地区：[1]湖南文理学院化学化工学院,湖南常德415000

出　　处：《湖南文理学院学报（自然科学版）》2016年第3期6-9,75,共5页Journal of Hunan University of Arts and Science(Science and Technology)

基　　金：湖南省教育厅一般项目(15C0954);湖南文理学院科学研究项目(14YB05);湖南文理学院大学生创新项目;湖南省十二五重点建设学科--应用化学资助

摘　　要：以4-溴-1,8-萘二甲酸酐为原料,经过Suzuki偶联反应、氨解反应,合成了一种水溶性的荧光探针,其结构经过1H NMR、MS进行了表征。利用荧光光谱、紫外光谱探讨了该探针对双氧水响应的性能。结果表明,该探针在纯水中对双氧水具有高选择性、高灵敏性,双氧水浓度在3.3×10^-8-1×10^-4 mol/L范围内探针对双氧水具有较好的线性,检测下限为0.1μg/mol。A water solution fluorescent probe is synthesized via Suzuki coupling reaction, oxidative reaction,ammonolysis reaction from 4-bromo-1, 8-naphthalic anhydride. Its structure is characterized by 1H NMR and MS.The spectroscopic properties, the target probe with H2O2 is investigated by the fluorescence spectrum andultraviolet spectrum. The results show that the probe can detect H2O2. The compound displays off/on ratio singles,highly selective and sensitive towards H2O2 in 100% water. The fluorescence intensity is proportional to theconcentration of glucose over a range of 3.3 × 10^-8～1 × 10^-4 mol/L, with a limit of detection of 0.1 μg/mol.

关 键 词：荧光探针 双氧水 比色 合成 

分 类 号：O657.3[理学—分析化学]