医源性肉毒毒素中毒的临床表现及救治原则  

The Clinical Manifestation and Treatment Principle of Intoxication of Iatrogenic Botulinum Toxin

作　　者：吴晓军[1] 金蓉[1] 刘颖[1] 王曼[1] 杨军[1] 王琳[1] 

机构地区：[1]上海交通大学医学院附属第九人民医院,上海市200011

出　　处：《组织工程与重建外科杂志》2016年第4期254-255,共2页Journal of Tissue Engineering and Reconstructive Surgery

摘　　要：目的探讨医源性肉毒毒素中毒的临床表现及救治原则。方法共收治了96例以美容为目的注射肉毒毒素后导致中毒的患者,采用肉毒抗毒素注射进行救治,并辅以支持疗法。结果根据中毒具体情况,在给予肉毒抗毒素、系统性支持疗法以及对症治疗后,能迅速控制病情,有效改善症状体征,预后良好,所有患者均未出现进一步中毒的严重反应。结论注射肉毒毒素中毒后,尽早给予肉毒抗毒素和相应支持治疗是十分必要和有效的。Objective To explore the clinical manifestation and treatment principle of intoxication of iatrogenic botulinum toxin. Methods Ninty-six patients with intoxication due to injection of botulinum toxin for beauty were treated with antitoxin injection and supporting treatments. Results Based on the specific intoxication, after making the treatment with antitoxin, systematic supporting treatments and purposeful treatments, the patients＇ symptoms and signs were quickly controlled with better prognosis and without further severe reaction. Conclusion It is very necessary and urgent to give the antitoxin and corresponding treatments after intoxication of botulinum toxin injection.

关 键 词：肉毒毒素 中毒 救治 

分 类 号：R622[医药卫生—整形外科]