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作 者:徐虹[1] 高晓丽[1] 胡丽楠[1] 闫明宇[1] 姜立坤[1] 范晨璐[1] 薄芳[2] 孙东旭[1] 李岩[1]
机构地区:[1]哈尔滨市疾病预防控制中心免疫规划所,黑龙江哈尔滨150056 [2]黑龙江省疾病预防控制中心免疫规划所,黑龙江哈尔滨150030
出 处:《现代预防医学》2016年第15期2844-2847,共4页Modern Preventive Medicine
基 金:黑龙江省卫生厅科研课题(课题编号2013309)
摘 要:目的 分析2010—2014年哈尔滨市先天风疹综合征(CRS)的监测结果。方法采用描述流行病学方法,对监测的CRS病例进行分析,并对监测指标进行评价。结果2010—2014年,哈尔滨市共报告CRS疑似病例611例,诊断为CRS的37例,发病率在6.88/10万~15.23/10万之间,年平均发病率为10.05/10万活产儿童;临床表现主要为先天性心脏病、听力损失和眼部疾病,患儿母亲均无明确风疹疫苗接种史;实验室诊断病例感染风疹病毒的时间集中在孕4~6周。结论我市CRS发病率仍在较高水平。应继续加强疫苗接种,开展育龄期妇女血清抗体水平监测,继续开展CRS病例监测,为制定CRS防控策略提供依据。Objective To analyze the congenital rubella syndrome (CRS) monitoring results from 2010 to 2014 in Harbin. Methods Description epidcmiology method was adopted to analyze the monitoring CRS cases and evaluate the monitoring indicators. Results 611 cases of CRS suspected cases were reported, and 37 cases diagnosed,2010 - 2014. The incidence of CRS was between 6.88/100 000 and 15.23/100 000. The annual incidence was 10.05/100 000. Clinical manifestations were mainly the expansion of congenital heart disease, hearing loss and eye disease. Mothers of the patients had no clear history of rubella vaccine. Among laboratory confirmed cases, rubella virus infection time focused at 4 to 6 weeks. Conclusion The incidence of the CRS in our city is still at a higher level. We should continue to strengthen the vaccination, and carry on childbearing age women serum antibody level monitoring. The monitoring of CRS case should be continued, and to provide the basis for CRS control and prevention.
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