北京市首钢地区鲍曼不动杆菌分布及耐药性分析  

Analysis of distribution and drug resistance of Acinetobacter baumannii in Shougang area in Beijing

作　　者：农金轻 张丹[2] 李锐[1] 郑燕蓉[1] 

机构地区：[1]北京大学首钢医院检验科,北京100144 [2]北京大学首钢医院急诊科,北京100144

出　　处：《中国医药科学》2016年第11期34-37,共4页China Medicine And Pharmacy

摘　　要：目的总结2010-2015年北京市首钢地区鲍曼不动杆菌分布及耐药性,以便为临床诊治提供依据。方法采集2010-2015年北京大学首钢医院的临床标本进行培养,并按照2010年美国CLSI标准及BD Phoenix 100细菌鉴定药敏分析仪进行判定分析。结果 2010-2015年北京市首钢地区鲍曼不动杆菌感染的科室主要有RICU、ICU、神外、呼吸科;鲍曼不动杆菌几乎只对多粘菌素完全敏感;近6年,其对复方磺胺甲噁唑（SMZ）的耐药率明显下降,从100%降至2015年的25%;对美罗培南、亚胺培南的耐药率却一路飙升至完全耐药。结论鲍曼不动杆菌感染广泛,耐药情况严重,临床应合理选择抗生素。Objective To provide basis for clinical diagnosis and treatment by summarizing the distribution and drug resistance of Acinetobacter baumannii from 2010 to 2015 in Shijingshan district of Beijing. MethodsClinical specimens were collected and cultured during 2010 to 2015 in our Hospital. The results were analyzed according to the CLSI standards in 2010 and BD Phoenix 100 of United States. Results Acinetobacter baumannii infection departments mainly included RICU, ICU, Neurosurgery department, Respiratory department in our Hospital, from 2010 to 2015, which was almost completely sensitive to polymyxin only. Nearly six years, acinetobacter baumannii to sulfamethoxazole（SMZ） resistance rates decreased significantly, from 100% down to 25% in 2015. Acinetobacter baumannii to meropenem and imipenem resistance rates soared to complete. Conclusion Acinetobacter baumannii infections were wide-spread, and its drug resistance was serious, which should be a reasonable choice of antibiotics in clinical.

关 键 词：鲍曼不动杆菌 分布 耐药性 地区 

分 类 号：R378[医药卫生—病原生物学]