颅脑CT灌注参数定量分析的准确性  

Accuracy of quantitative analysis of cerebral CT perfusion parameters

作　　者：周瑞臣[1] 李伟[2] 李健[1] 惠颖[1] 张文艳[1] 郭庆乐[1] 

机构地区：[1]开滦总医院CT室 [2]中国人民解放军65367部队医院防疫所

出　　处：《中国介入影像与治疗学》2016年第8期477-480,共4页Chinese Journal of Interventional Imaging and Therapy

基　　金：唐山市科技计划项目(14130227a)

摘　　要：目的探讨灌注图像减薄处理前后灌注参数的稳定性。方法连续选取28例接受颅脑CT灌注成像的患者,均采用Cine full 1.0s扫描模式,在50s内连续曝光扫描。按照所得图像是否经过剪薄处理分为两组,一组为未经剪薄处理的原始图像,为A组;另一组将原始图像进行1/2减薄处理,为B组。由2名影像诊断医师在基底节层面同时测量A、B两组灰质区、豆状核区及白质区的灌注参数脑血流量(CBF)、脑血容量(CBV)及平均通过时间(MTT)并进行比较。结果 A组脑灰质区、豆状核区及脑白质区MTT均低于B组,CBF均高于B组,两组间差异有统计学意义(P均<0.05);A、B两组脑灰质区、豆状核区、白质区CBV差异无统计学意义(P均>0.05)。结论不同的颅脑灌注扫描方式得到的灌注参数不同,以MTT及CBF更为显著。Objective To explore the stability of perfusion parameters by comparing the perfusion parameters between o- riginal images and cutting the half of original images. Methods Totally of 28 cases underwent brain perfusion scan. All pa- tients were scanned with cine scan 1.0 s mode, and were continuous scanning for 50 s. The original images were defined as A group and the group which were cut the half of original images were as B group. The perfusion parameters such as mean transit time （MTT）, cerebral blood flow （CBF）, and cerebral blood volume （CBV） were measured and compared in the ar- ea of cerebral gray matter, lenticular nucleus and cerebral white matter. Results The MTT were significant lower in A group than B group in the area of cerebral gray matter, lenticular nucleus and cerebral White matter （all P〈0.05） ; the CBF were significant higher in A group than B group in the area of cerebral gray matter, lenticular nucleus and cerebral white matter （all P〈0.05） ; CBV had no statistical significant between A group and B group. Conclusion The different ways of brain perfusion scan would get to different perfusion parameters, especially the MTT and CBF.

关 键 词：体层摄影术 X线计算机 脑 灌注成像 辐射剂量 

分 类 号：R816.1[医药卫生—放射医学]