医院获得性革兰阳性球菌血流感染病原菌分布及影响预后危险因素分析  

Hospital-acquired bloodstream infections pathogens were gram positive coccus distribution and the analysis of risk factors affecting prognosis

作　　者：杨小兰[1] 李伟强[1] 黄春花[1] 张必辉 黄东新 林伟朋 

机构地区：[1]惠州市第三人民医院检验科,广东惠州516002

出　　处：《中国实验诊断学》2016年第6期919-922,共4页Chinese Journal of Laboratory Diagnosis

摘　　要：目的研究住院患者革兰阳性球菌血流感染菌群分布以及影响患者预后的危险因素,为院内感染的防治提供临床资料。方法回顾性分析我院128例住院患者革兰阳性球菌血流感染情况,并根据预后分为生存组(96例)、死亡组(32例),回归分析影响预后的危险因素。结果 128株革兰阳性球菌菌群分布凝固酶阴性葡萄球菌58株,占45.3%;金黄色葡萄球菌21株,占16.4%;屎肠球菌15株,占11.7%;住院时间、机械通气、留置导尿管、长期透析、APACHEⅡ评分、免疫抑制剂、激素长期使用均为预后不良的独立危险因素,均有统计学意义(P<0.05)。结论对血流感染的独立危险因素进行有效的控制能有效的减少血流感染发生机率。Objective To study the risk factors for the distribution of bloodstream infections in hospitalized patients with gram positive bacteria,and to provide clinical data for the prevention and treatment of nosocomial infection. Methods retrospective analysis of 128 cases of hospitalized patients with gram positive bacterial blood infection,and according to the prognosis of the patients were divided into survival group （96 cases）, death group （32 cases）, regression analysis of risk factors affecting prognosis. Results 128 leather gram positive cocci bacteria group distribution of coagulase negative staphylococcus （58 strains, accounted for 45.3%;21 strains of Staphylococcus aureus, 16.4%; 15 strains of Enterococcus faecium, 11.7%; hospitalization time, mechanical ventilation, indwelling catheter, long-term dialysis, APACHE II score, immune suppression agent, hormone use for a long time were the independent risk factors of poor prognosis. There was statistically significant（P〈0.05）. Conclusion effective control of the independent risk factors of bloodstream infection can effectively reduce the incidence of bloodstream infection.

关 键 词：革兰阳性球菌 菌群分布 预后 危险因素 

分 类 号：R446.5[医药卫生—诊断学]