罂粟碱用于治疗分娩时宫颈水肿产妇的疗效分析  

Analysis of therapeutic effects of Papaverine for the parturients of cervical edema in childbirth

作　　者：林姬[1] 赵林桦[1] 谢芳[1] 陈灼英[1] 林立姮[1] 

机构地区：[1]福建医科大学附属闽东医院妇产科,福建福安355000

出　　处：《中国医药科学》2016年第10期7-9,13,共4页China Medicine And Pharmacy

基　　金：福建省科技开发指导性计划项目(200819)

摘　　要：目的观察和分析罂粟碱用于治疗足月产妇分娩时宫颈水肿的疗效。方法选择2014年1月-2015年12月收治的110例在分娩过程中出现宫颈水肿的产妇作为研究对象,采用随机数字表分组的方法分为实验组和对照组,每组55例。实验组静脉注射罂粟碱,对照组静脉注射安定。对比用药治疗后实验组和对照组产妇宫颈水肿情况、宫口扩张全开所需时间、新生儿窒息情况以及剖宫产率。结果治疗后,实验组产妇宫颈水肿消退总有效率明显高于对照组,差异具有统计学意义（P〈0.05）;实验组宫口全开时间短于对照组,差异有统计学意义（P〈0.05）;实验组阿氏评分总分小于4分的新生儿显著少于对照组,差异具有统计学意义（P〈0.05）;实验组产妇剖宫产率明显低于对照组,差异具有统计学意义（P〈0.05）。结论罂粟碱能有效治疗产妇分娩过程中的宫颈水肿,降低剖宫产率,对胎儿无明显呼吸抑制作用,值得在临床上推广应用。Objective To observe and analyze the therapeutic effects of Papaverine for term parturients with cervical edema in childbirth. Methods One hundred and ten cases of parturients who developed cervical edema in childbirth in our hospital from January 2014 to December 2015 were as research objects. They were randomly divided into experimental group and control group. There were 55 cases in each group. Experimental group was given Papaverine by injection. Control group was diazepam by injection. To analyze and compare the cervical edema, the time of uterine cervix dilatation, the neonatal asphyxia and the rate of cesarean section. Results The total effective rate of cervical edema subsiding in experimental group was obviously higher than in control group. The differences had remarkable statistical significance（P〈0.05）.The time of uterine cervix dilatation in experimental group was shorter in control group.The differences had statistical significance（P〈0.05）. The number of the newborn with less than four in experimental group was distinctly less than in control group. The differences had remarkable statistical significance（P〈0.05）.The rate of cesarean section in experimental group was lower than in control.The differences had remarkable statistical significance（P〈0.05）. Conclusion Papaverine could effectively treat the cervical edema in childbirth, reduce the rate of cesarean section, and didn＇t inhibit the respiration of fetus. Thus,it is worth to popularize and apply Papaverine on clinic.

关 键 词：罂粟碱 安定 宫颈水肿 阿氏评分 

分 类 号：R714.4[医药卫生—妇产科学]