肝细胞肝癌的动态三维超声造影成像质量的影响因素分析  

Imaging quality of dynamic three-dimensional contrast-enhanced ultrasonography in hepatocellular carcinoma:an analysis of influencing factors

作　　者：毛丽娟[1] 王文平[1] 丁红[1] 薛立云[1] 范培丽[1] 李翠仙[1] 韩红[1] 

机构地区：[1]复旦大学附属中山医院超声科,上海200032

出　　处：《中国临床医学》2016年第3期273-277,共5页Chinese Journal of Clinical Medicine

基　　金：国家自然科学基金(81371577;81571675)~~

摘　　要：目的:探讨肝细胞肝癌(HCC)动态三维超声造影(3D-CEUS)成像质量的影响因素。方法:回顾分析经病理及临床随访确诊的63例HCC患者共67个病灶的73次动态3D-CEUS资料。对动态3D-CEUS的成像质量进行评分,分析病灶是否初发、位置、大小、深度、血供、患者动脉期呼吸配合情况及肝脏有否硬化对HCC动态3D-CEUS动脉期成像质量的影响。结果:73次HCC动态3D-CEUS动脉期成像质量评3分、2分、1分分别为51次(69.9%)、13次(17.8%)和9次(12.3%)。病灶是否初发、位置、大小、肝脏有否硬化对HCC动态3D-CEUS成像质量的影响不明显;病灶深度(P=0.028)、血供(P=0.000)和患者动脉期呼吸配合情况(P=0.000)明显影响HCC动态3D-CEUS的成像质量。结论:病灶深度>8cm、乏血供和患者动脉期呼吸配合不佳可致HCC的动态3D-CEUS动脉期成像质量下降;病灶是否初发、位置、大小和肝脏是否硬化对HCC的动态3D-CEUS动脉期成像质量无明显影响。Objective：To investigate the influencing factors of the imaging quality of dynamic three-dimensional contrast-enhanced ultrasonography（3D-CEUS）in hepatocellular carcinoma（HCC）.Methods：73 dynamic 3D-CEUS data of 67 lesions in 63 HCC patients confirmed by pathology and clinical follow-up were retrospectively analyzed.The imaging quality of dynamic 3D-CEUS was scored.Effects of various factors on the imaging quality of HCC dynamic 3D-CEUS arterial phase were analyzed：whether the lesion was primary,location of the lesion,size,depth,blood supply,patients＇ breathing during the arterial phase and whether there was liver cirrhosis.Results：The imaging quality of dynamic 3D-CEUS in the arterial phase of 73 HCC was assessed as 3 points,2 points and 1 point for 51 times（69.9%）,13 times（17.8%）and 9 times（12.3%）respectively.Whether the lesion was primary or not,location of the lesion,size and whether there was liver cirrhosis had no significant influence on the imaging quality of HCC dynamic 3D-CEUS.Depth of the lesion,blood supply and patients＇ breathing during the arterial phase had significant influence on the imaging quality of HCC dynamic 3D-CEUS（P=0.028,0.000,and 0.000,respectively）.Conclusions：Depth of the lesion more than 8cm,lack of blood supply and patients＇ poor breathing during the arterial phase could affect the imaging quality of HCC dynamic 3D-CEUS,whereas whether the lesion is primary or recurrent,location of the lesion,size and liver cirrhosis have no significant influence on the imaging quality of HCC dynamic 3D-CEUS.

关 键 词：超声检查 三维超声造影 微气泡 肝细胞肝癌 

分 类 号：R445.1[医药卫生—影像医学与核医学]