中老年人群人体成分与血脂及肝功能水平的相关性  

Relationship between serum lipid,liver function and body composition in middle-aged and elderly people

作　　者：黄昌华 刘小立[2] 周继昌[2] 孙仕强 许佳章[2] 周小英[2] 徐健[2] 龚春梅[2] 

机构地区：[1]深圳市麒麟山疗养院体检中心,广东深圳518055 [2]深圳市慢性病防治中心分子生物室,广东深圳518020

出　　处：《职业与健康》2016年第13期1826-1829,共4页Occupation and Health

基　　金："十二五"科技支撑计划项目(2012BAI02B02);深圳市科技计划项目(201401070)

摘　　要：目的分析中老年人群中人体成分与血脂、肝功能指标之间的相关性。方法选择深圳市某体检中心2013年7月—2014年1月排除了心肌梗死病史、肿瘤病史、严重感染、肝功能不全及无法独自站立的检查者后共925例。使用Inbody230人体成分仪对人体成分进行测定,主要包括体质指数(BMI)、体重、骨骼肌、蛋白质、体脂肪、矿物质含量、体脂百分比(%)、身体水分含量、体脂肪、去脂体重、腹部肥胖程度等指标,同时收集血清测定血脂及肝功能指标。结果除了体脂肪不受性别影响外,其余指标男女之间的体成分差异均有统计学意义(均P<0.01)。正常体重、超重、肥胖之间的成分BMI与甘油三酯(TG)呈正相关,体脂肪与胆固醇(TC)、TG、低密度脂蛋白胆固醇(LDL-C)均呈正相关关系,体脂百分比与TC、LDL、高密度脂蛋白胆固酬(HDL-C)呈正相关,腹部肥胖程度与TC、TG、LDL呈正相关,而矿物质含量、身体水分含量及去脂体重与TG均呈正相关,与其余3项负相关。BMI、腹部肥胖程度、矿物质量、身体水分含量及去脂体重与丙氨酸转氨酶(ALT)、天冬氨酸转氨酶(AST)呈正相关,体脂肪与ALT呈正相关。结论中老年人群人体成分与血脂、肝功能水平密切相关。通过人体成分分析,可早期发现血脂和肝功能异常,指导中老年人健康的生活方式,尽早预测、发现营养相关性疾病,协助临床诊断。[ Objective ] To explore the relationship between serum lipid, liver function and body composition in middle-aged and elderly people. [ Methods] After the people with the history of myocardial infarction, tumors, severe infection and hypohepatia and those cannot stand alone have been excluded, 925 middle-aged and elderly people received health examination in a medical examination center of Shenzhen City from July 2013 to January 2014 were recruited in the study. Body composition was measured by Biospace Inbody 230, including the body mass index （BMI）, body weight, skeletal muscle, protein, body fat, mineral content, body fat percentage （%）,body moisture content, lean body weight, and abdominal obesity. Meanwhile, the serum samples were collected to detect the serum lipid and liver function indicators. [Results] Except the body fat, the differences in the other body composition indicators were statistically significant between sex groups （P〈0.01）. BMI （normal weight, overweight, obesity） was positively correlated with triglyeeride （TG）. The body fat was positively correlated with cholesterol （TC）, TG, and low density lipoprotein cholesterol （LDL-C）. The body fat percentage was positively correlated with TC, LDL and high density lipoprotein cholesterol （HDL-C）. The abdominal obesity was positively correlated with TC, TG and LDL. The mineral content, body moisture content and lean body weight were positively correlated with TG, while were negatively correlated with TC, HDL-C and LDL. The BMI, abdominal obesity, mineral content, body moisture content and lean body weight were positively correlated with alanine aminotransferase （ALT） and aspartate aminotransferase （AST）.The body fat was positively correlated with ALT. [Conclusion] Body composition has a close relationship with serum lipid and liver function in middle-aged and elderly people. The body composition analysis can be used in the early detection of blood lipids and liver dysfunction, guiding the healthy lifestyle of

关 键 词：人体成分 血脂 肝功能 

分 类 号：R181.3[医药卫生—流行病学]