Meso-1,2,3,4-四氯丁烷的正辛醇/水分配系数的测定  

Determination of the n-Octanol/Water Partition Coefficient of Meso-1,2,3,4-tetrachlorobutane

作　　者：谭头云[1] 孙剑英[1] 许来威[1] 

机构地区：[1]浙江省化工研究院有限公司,浙江杭州310023

出　　处：《浙江化工》2016年第7期45-47,共3页Zhejiang Chemical Industry

摘　　要：建立摇瓶法测定Meso-1,2,3,4-四氯丁烷的正辛醇/水分配系数分析方法。正辛醇中Meso-1,2,3,4-四氯丁烷含量采用气相色谱法直接测定,水相中Meso-1,2,3,4-四氯丁烷含量采用三氯甲烷萃取,气相色谱法测定。当正辛醇与水体积比为2:1时,lgP_(ow)为2.6;体积比为1:1时,lgP_(ow)为2.7;体积比为1:2时,lgP_(ow)为2.8;lgP_(ow)平均值为2.7。该方法简单可靠,符合OECD 107要求,适用于Meso-1,2,3,4-四氯丁烷的正辛醇/水分配系数的测定。The analytical method for determination of the n-octanol/water partition coefficient of Meso-1,2,3,4-tetrachlorobutane by shake flask method was established. The Meso-1,2,3,4-tetrachlorobutane in noctanol was determined by gas chromatography, the Meso-1,2,3,4-tetrachlorobutane in water was extracted by chloroform and was determined by gas chromatography. When the volumetric ratio of n-octanol/water was2：1, lgPowwas 2.6, the volumetric ratio of n-octanol/water was 1：1, lgPowwas 2.7, the volumetric ratio of noctanol/water was 1：2, lgPowwas 2.8. The average value of lgPowwas 2.7. The method was simple and reliable,conformed to the requirement of OECD 107, and could be suitable for determination of the n-octanol/water partition coefficient of Meso-1,2,3,4-tetrachlorobutane.

关 键 词：Meso-1 2 3 4-四氯丁烷 摇瓶法 气相色谱 萃取 

分 类 号：O645.1[理学—物理化学]