针灸治疗在颅脑损伤早期的疗效观察  

Observation on curative effects of acupuncture for early Craniocerebral injury

作　　者：郭杵强[1] 张毅敏[2] 彭志强[1] 

机构地区：[1]广州市番禺区中医院,广东511400 [2]暨南大学,广东510630

出　　处：《齐齐哈尔医学院学报》2016年第13期1679-1681,共3页Journal of Qiqihar Medical University

基　　金：广东省广州市科技计划项目;项目编号:2010GN-E00221

摘　　要：目的探讨颅脑损伤早期,针灸治疗的临床疗效。方法将60例颅脑损伤致昏迷的患者按随机数字表法分为实验组30例和对照组30例。对照组采用西医常规治疗,实验组在此基础上,于术后第2天给予针灸治疗,疗程4周。观察两组治疗前后的格拉斯哥昏迷评分(GCS)变化、治疗后格拉斯哥预后评分(GOS)及治疗前、术后第1、3、7天的血清S-100B蛋白及血清神经元特异性烯醇化酶(NSE)浓度变化。结果治疗后两组患者的GCS评分均较前提高,差异有统计学意义(P<0.05),但实验组的提高程度优于对照组,差异有统计学意义(P<0.05);4周后,实验组GOS评分优于对照组,差异有统计学意义(P<0.05);术后第7天两组NSE、S-100B蛋白含量均出现明显降低,差异有统计学意义(P<0.05);但实验组的下降程度优于对照组,差异有统计学意义(P<0.05)。结论早期针灸治疗可提高颅脑损伤患者的GCS、GOS评分,降低血清NSE、S-100B蛋白的浓度,具有促醒及改善预后的作用。Objective To explore the clinical curative effects of acupuncture for early Craniocerebral injury. Methods Sixty cases of patients with coma caused by Craniocerebral injury were divided into the observation group （n =30） and the control group （n = 30） according to the random number table. The control group was given conventional western medicine for treatment, while the observation group was given acupuncture in addition from the second day after the surgery on the basis of the control group. The curative course was 4 weeks. The two groups were observed for Glasgow coma scale （GCS） before and after the treatments, post treatment Glasgow outcome scale （GOS）, concentration of serum S -100B protein and serum neuron specific enolase （NSE） before treatment and on postoperative 1, 3and 7days. Results GCS scores were improved in both of the two groups after the treatments, with statistically significant differences （P 〈 0. 05）. The improvement degree was larger in the observation group than that of the control group, with statistically significant differences （ P 〈 0. 05 ）. GOS scores in the observation group was superior to that of the control group in the fourth week after the treatment, with statistically significant differences （P 〈0. 05）. NSE and S- 100B proteins in both of the two groups were decreased on postoperative 7day, with statistically significant differences （P 〈0. 05）. The declined degree of the observation group was larger than that of the control group, with statistically significant differences （P 〈 0. 05）. Conclusions Early acupuncture treatment can improve the GCS and GOS scores in patients with Craniocerebral injury, reduce serum NSE and S- 100B protein concentration, has the effect of wake promotion and prognosis improvement.

关 键 词：针灸 颅脑损伤 神经元特异性烯醇化酶 S-100B蛋白 格拉斯哥昏迷评分 

分 类 号：R277.751.2[医药卫生—中医学]