慢性阻塞性肺疾病合并阻塞性呼吸暂停综合征夜间发生呼吸暂停的时间调查  

Investigation on the occurrence time of apnea of patients with chronic obstructive pulmonary disease combined obstructive sleep apnea syndrome

作　　者：梁凤英[1] 肖鑫[1] 黄秀华[1] 

机构地区：[1]南方医科大学附属小榄医院呼吸内科,广东528415

出　　处：《齐齐哈尔医学院学报》2016年第13期1736-1738,共3页Journal of Qiqihar Medical University

摘　　要：目的探讨慢性阻塞性肺疾病（COPD）合并呼吸暂停综合征患者夜间呼吸暂停发作频率最高的时间段,并运用结果来指导临床护理,从而减少意外事件发生,提高患者的生活质量。方法随机抽取南方医科大学附属小榄医院2013年1月至2014年12月的100例COPD合并阻塞性睡眠呼吸暂停综合征的患者,全部经过多导睡眠仪（PSG）检查,均连续监测患者至少7 h睡眠时间的鼻气流、血氧饱和度（SPO2）,胸腹呼吸运动,脑电图,颌下肌群、肌电图等,得出其夜间发生呼吸暂停的时间,并运用比较法分析得出发生率最高的时间段。结果 OSAHS患者在各年龄段（〈45岁,45~60岁,60~80岁）中分布差异有统计学意义（P〈0.05）;男性各年龄段患者多于女性患者,差异具有统计学意义（P〈0.05）。在轻度患者中,2：00~4：00为发病最高时间段,发生率为59%,其次为4：00~6：00,发生率为21%;在中度患者中,发病最高的时间段为2：00~4：00,发生率为42%,其次为0：00~2：00,发生率为31%。在重度患者中,发生率最高为2：00~4：00,发生率为30.6%,但各个时间段发病无明显差异性,各个时间段发病均较高。结论年龄越大,OSAHS发病率越高,且在各个其他年龄段,均为2：00~4：00为发病最高时间段,男性各年龄段患者多于女性患者。Objective To investigate the time period of respiratory apnea episodes at night in patients with COPD combined with respiratory apnea syndrome, and use the results to guide clinical nursing, so as to reduce the occurrence of accidents and improve the quality of life of patients. Methods A total of 100 patients with obstructive sleep apnea syndrome, got therapy in our hospital from January 2013 to December 2014, were randomly selected. All of the patients were examined by PSG, and the patients were monitored for at least 7h to obtain the indexes nasal airflow, SPO2, chest abdominal breathing exercise, EEG, EMG and so on. Based on the indexes to calculated the time the respiratory apnea occurring, and find out the time period when the respiratory apnea occurring with the highest frequency. Results The difference of distribution of OSAHS in each age group （less than 45 years old, 45 - 60 years old, 60 - 80 years old） was statistically significant （ P 〈 0. 05 ）. Among the patients, males were more than females in each age group, the difference was statistically significant （P 〈 0. 05 ）. In mild patients, 2：00am to 4：00am was the highest incidence time, the incidence rate was 59%, followed by 4：00am to 6：00am, and the incidence rate was 21%. In moderate patients the highest incidence time was during 2：00am to 4：00am, the incidence rate was 42%, followed by the period 0：00am to 2：00am, the occurrence rate was 31%. In severe cases, the highest incidence time period was between 2：00am and 4：00am, the incidence rate was 30.6%, but there was no significant difference between each time period. Conclusions The older the age, the higher the incidence of OSAHS, and in all age groups the time 2：00am to 4：00am is the highest time period, there are more men than women suffering OSAHS.

关 键 词：肺疾病 慢性阻塞性 睡眠呼吸暂停 阻塞性 时间调查 

分 类 号：R454.2[医药卫生—治疗学]