新疆地区公共场所从业人员戊型肝炎病毒感染血清学调查分析  

Serological survey on hepatitis E virus infection of public health practitioners in Xinjiang region

作　　者：武军元[1,2] 侯向萍 

机构地区：[1]塔里木大学动物科学学院,新疆阿拉尔843300 [2]新疆生产建设兵团塔里木畜牧科技重点实验室,新疆阿拉尔843300 [3]新疆维吾尔自治区阿拉尔市人民医院检验科,新疆阿拉尔843300

出　　处：《吉林大学学报（医学版）》2016年第4期827-829,共3页Journal of Jilin University：Medicine Edition

基　　金：国家自然科学基金资助课题(31160513)

摘　　要：目的:调查新疆地区公共场所从业人员戊型肝炎病毒(HEV)感染的状况及感染的影响因素,为当地戊型肝炎防控提供依据。方法:对新疆地区不同公共场所从业人群,采用随机抽样的方式采集血清样品1 720份,应用双抗原夹心酶联免疫法检测血清样本中抗HEV-IgG抗体,分析不同性别、年龄和职业人群间戊型肝炎感染率的差异。结果:受试对象1 720人中有440例抗HEV-IgG抗体阳性,阳性率为25.58%,其中男性阳性率为27.99%,女性阳性率为23.35%,且随着年龄的增长,抗体阳性率逐渐增高,不同年龄段人群抗HEV-IgG抗体阳性率比较差异有统计学意义(χ2=118.262,P=0.000);不同类别从业人员戊型肝炎感染率比较差异有统计学意义(χ2=98.262,P=0.000),抗HEV-IgG抗体阳性率由高到低依次为家畜屠宰工人81.53%,家畜及肉品销售人员79.37%,餐饮服务人员30.00%,超市服务人员11.21%,其他人群9.03%。结论:新疆地区公共场所从业人员戊型肝炎感染率相对较高,职业、年龄和性别是影响戊型肝炎感染率的主要因素。Objective：To investigate the infection status and influencing factors of hepatitis E virus infection among different occupational populations in Xinjiang region,and to provide a available evidence for control of hepatitis E.Methods：A randomly sampling survey was carried out in the population of public health practitioners,the serum IgG antibodies against hepatitis E virus in 1 720 samples were tested by indirect enzyme-linked immunosorbent assay,and the experimental data was analyzed with SPSS 19.0software;the differences of infection rates between genders,ages and occupations were analyzed.Results：Among 1 720 subjects,440persons were anti-HEV IgG positive,and the total positive rate was 25.58%;the positive rate of males（27.99%）was higher than that of females（23.35%）,and the IgG positive rate was increased along with the age;there were significant differences of the anti-HEV-IgG antibody positive rates between the populations with different ages（χ^2=118.262,P=0.000）.There was a statistically significant difference of infection rate of hepatitis E between different occupational populations（χ^2=98.262,P=0.000）,the slaughterman had the highest positive rate（81.53%）,followed by the livestock and meat salesperson（79.37%）,food service population（30%）,supermarket population（11.21%）and others（9.03%）.Conclusion：The hepatitis E infection rate is high among the public health practitioners in Xinjiang region,and occupation,age and gender are the major influencing factors of hepatitis E infection rate.

关 键 词：戊型肝炎病毒 公共卫生 血清学调查 酶联免疫吸附测定 

分 类 号：R512.6[医药卫生—内科学]