A Mitochondrial DNA A8701G Mutation Partly Associated with Maternally Inherited Hypertension and Dilated Cardiomyopathy in a Chinese Pedigree  

作　　者：Ye Zhu Xiang Gu Chao Xu 

机构地区：[1]Department of Cardiology, Clinical Northern People's Hospital, Medical College of Yangzhou University, Yangzhou, Jiangsu 225001, China [2]Department of Biostatistics and Bioinformatics, Center for Bioinformatics and Genomics, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA 70112, USA

出　　处：《Chinese Medical Journal》2016年第15期1890-1890,共1页中华医学杂志（英文版）

摘　　要：Thank you for your valuable comments on our paper, ＂A Mitochondrial DNAA8701G Mutation Associated with Maternally Inherited Hypertension and Dilated Cardiomyopathy in a Chinese Pedigree.＂We agree with this conclusion that this case requires profound confirmation of the pathogenicity of the m.8701A〉G variant, all patients need to be investigated for multiorgan involvement, and long-term electrocardiograph data need to be presented. However, it is clinically not easy to implement the comprehensive testing for all of the related patients.Thank you for your valuable comments on our paper, ＂A Mitochondrial DNAA8701G Mutation Associated with Maternally Inherited Hypertension and Dilated Cardiomyopathy in a Chinese Pedigree.＂We agree with this conclusion that this case requires profound confirmation of the pathogenicity of the m.8701A〉G variant, all patients need to be investigated for multiorgan involvement, and long-term electrocardiograph data need to be presented. However, it is clinically not easy to implement the comprehensive testing for all of the related patients.

分 类 号：R54[医药卫生—心血管疾病]