不规则抗体筛查在临床输血患者中的检出结果及分析  

Detection result and analysis of irregular antibody screening in clinical blood transfusion patients

作　　者：张楠 屈跃军 白振宇 

机构地区：[1]平顶山市平煤神马医疗集团总医院输血科,467099

出　　处：《中国实用医药》2016年第17期39-40,共2页China Practical Medicine

摘　　要：目的探讨并分析不规则抗体筛查在临床输血患者中的检出结果 ,为保证临床输血安全减少输血反应及临床疑难输血提供依据。方法 17521例住院患者,应用微柱凝胶抗球蛋白法筛查其血清中不规则抗体,对阳性患者进行抗体特异性检测并分析。结果 17521例受血者不规则抗体阳性率为0.35%(61/17521),检出血型同种不规则抗体61例。男性阳性检出率为0.30%(21/6952),女性阳性检出率为0.38%(40/10569)。结论输血前不规则抗体筛检能发现有临床意义的不规则抗体,特别是对血液病、肿瘤、多次输血及有多次妊娠史患者可提前预警,以保证患者输血安全。Objective To investigate and analyze detection result of irregular antibody screening in clinical blood transfusion patients, and to provide reference for ensuring clinical blood transfusion safety and reducing blood transfusion reaction and clinical transfusion difficulty. Methods Microcolumn gel test was applied in irregular antibody screening for 17521 hospitalized patients, and their antibody specificity was detected and analyzed. Results Positive rate of irregular antibody was 0.35%（61/17521） in 17521 patients, as 61 cases with irregular antibody as blood type. Positive detection rate in male was 0.30%（21/6952）, and it was 0.38%（40/10569） in female. Conclusion Irregular antibody screening before blood transfusion can detect irregular antibody with clinical significance, which shows proactive warning especially for patients with blood disease, tumor, multiple transfusions and multiple pregnancies, so as to ensure blood transfusion safety in patients.

关 键 词：不规则抗体 筛查 微柱凝胶法 输血安全 

分 类 号：R457.1[医药卫生—治疗学]