冠脉追踪技术结合单能量成像去运动伪影的临床应用  

Clinical Application of Gemstone Spectral CT Snapshot Freeze Motion Correction Algorithm on Optimal Monochromatic Energy Level in Coronary Angiography

作　　者：高剑波[1] 蒋耀军[1] 刘杰[1] 吴艳[1] 侯平[1] 查开继[1] 

机构地区：[1]郑州大学第一附属医院放射科,河南郑州450052

出　　处：《中国医疗设备》2016年第7期12-15,共4页China Medical Devices

摘　　要：目的探讨能谱CT在最佳单能量（65 ke V）下冠脉追踪技术（SSF）对受试者冠状动脉血管成像（CCTA）质量的影响。方法 30例疑似冠心病的患者行冠状动脉成像的患者,均未服用任何控制心率的药物等附加条件。每个受试者的CT冠状动脉成像图像均使用STD算法与SSF两种方法进行对比重建,其中是对85%期相的图像进行重建。由我科一名做冠脉成像血管重建的医师进行图像质量的客观评价,利用后处理工作站进行相关血管的CT值以及噪声的测量,对其两种算法的主要血管的CT值、噪声、SNR以及CNR进行独立样本t检验,比较65 ke V下两种算法的各项指标差异;另外,由我科两名有做冠脉成像血管重建的医师进行图像质量的主观评分,评分标准采用5分制,对图像质量的主观评分采用配对秩和检验。结果 65 ke V下STD算法与SSF算法的主动脉根部、左冠主干、前降支近段、左回旋支近段及右冠近段的CT值、噪声、SNR及CNR的值均无统计学意义（t值为-0.547~1.418,P值均﹥0.05）;左冠主干（分别为4.7±0.5和4.9±0.3,Z=-2.232a,P=0.026）,前降支（分别为4.4±0.4和4.5±0.4,Z=-2.68a,P=0.007）,左回旋支（分别为4.1±0.6和4.3±0.4,Z=-2.668a,P=0.008）及右冠状动脉（分别为3.5±0.6和4.5±0.4,Z=-4.785a,P=0）评分在两种算法之间均有统计学意义。结论与STD算法比较,SSF在不失真的情况下能够明显提高CT冠状动脉成像的质量,利于对冠状动脉的血管病变诊断。Objective To investigate the effect of application of snapshot freeze（SSF） motion correction algorithm on the image quality of coronary CT angiography（CCTA） on optimal monochromatic energy level. Methods Thirty consecutive patients who underwent coronary CTA without heart rate control were selected. All of the CCTA images were reconstructed by the means of both STD and SSF motion correction, which was about 85% period of image reconstruction. An experienced radiologist made use of post-processing workstation to measure the value of CT about blood vessel the noise of image. Comparisons of variables about the CT value of the major blood vessels, noise, SNR and CNR were performed with t test.Image quality and interpretability of STD and SSF reconstructions were compared.CCTA images were interpreted with 5-points score system by two experienced radiologists. The image qualities were assessed on per-artery and per-segment level,and interpretability was performed on persegment, per-artery, and per-patient levels. Comparisons of variables were performed with paired Wilcoxon rank sum test. Results The STD and SSF reconstructions of three main vessels showed no significant differences in CT value. The image qualities were higher with the use of SSF reconstructions than STD reconstructions on LM [（4.7±0.5）,（4.9±0.3）, Z=-2.232 a, P=0.026], LAD [（4.4±0.4）,（4.5±0.4）, Z=-2.68 a, P=0.007], LCX [（4.1±0.6）,（4.3±0.4）, Z=-2.668 a, P=0.008], and RCA [（3.5±0.6）,（4.5±0.4）, Z=-4.785 a, P=0] levels. Conclusion The use of SSF motion correction algorithm improved image quality and interpretability or coronary CTA.

关 键 词：冠状动脉血管 体层摄影术 X线计算机 冠脉追踪技术 

分 类 号：R816.1[医药卫生—放射医学]