汞中毒患者肾脏损伤症状调查研究  

Symptoms of kidney damage in mercury poisoning patients

作　　者：曾军杰[1] 陈新 

机构地区：[1]河南省医学会,郑州450003 [2]河南省职业病防治研究院

出　　处：《中国实用医刊》2016年第14期17-18,共2页Chinese Journal of Practical Medicine

基　　金：十二五国家科技支撑计划课题(2014BAI12B01)；国家重点临床专科建设项目(2011-17)。

摘　　要：目的：调查汞中毒伴肾脏损伤患者不适症状，分析汞中毒伴肾脏损伤患者的有关症状及指标。方法选取河南省职业病防治研究院2010年至2015年汞中毒住院患者93例，依据肾脏损伤入选标准分为肾脏损伤组和无肾脏损伤组，询问两组患者症状、体格检查指标进行相关统计学分析，有统计学差异的指标为汞中毒伴肾脏损伤患者阳性指标。结果肾脏损伤组与无肾脏损伤组进行比较，头痛（χ2＝4.86，P ﹤0.05）、精神性格改变（χ2＝4.31，P ﹤0.05）、尿量增多（χ2＝5.56，P ﹤0.05）、水肿（χ2＝5.17，P ﹤0.05）差异均有统计学意义；头晕（χ2＝0.52，P ﹥0.05）、记忆力减退（χ2＝0.01，P ﹥0.05）、肌肉疼痛（χ2＝1.394，P ﹥0.05）、失眠（χ2＝2.54，P ﹥0.05）、眼颤（χ2＝0.65，P ﹥0.05）、手颤（χ2＝1.10，P ﹥0.05）、舌颤（χ2＝1.53，P ﹥0.05）差异均未见统计学意义，提示头痛、精神性格改变、尿量改变、水肿为汞中毒伴肾脏损伤患者有意义的指标。结论头痛、精神性格改变、尿量改变、水肿为汞中毒伴肾脏损伤患者阳性症状。Objective To investigate and analyze the signs and symptoms of renal injury patients with mercury poisoning. Methods From 2010 to 2015,93 patients with mercury intoxication in Henan institute of occupational disease prevention and control were selected. According to kidney injury,the participants were divided into renal injury group and non renal injury group. Statistical analysis was em-ployed to detect positive indicators with symptoms,physical examination indicators between different uri-nary mercury concentration groups. Results There was no significant difference in dizziness,the memo-ry loss,muscle pain,insomnia,nystagmus,hand-trembling,tongue-trembling between the two groups. There were significant differences in headache（χ2 = 4. 86,P ﹤ 0. 05）,changes of spirit and character （χ2 = 4. 31,P ﹤ 0. 05）,polyuria（χ2 = 5. 56,P ﹤ 0. 05）,edema（χ2 = 5. 1,P ﹤ 0. 05）,suggesting that these were influencing factors of renal injury patients with mercury poisoning. Conclusions Headache, mental character,urine volume change and edema are positive symptoms in renal injury patients with mercury poisoning.

关 键 词：汞中毒 肾脏损伤 精神性格改变 

分 类 号：R692[医药卫生—泌尿科学]