非离子型对比剂对肾功能的影响  

Clinical influence of non-ionic contrast agents on renal function

作　　者：甘璐[1] 尤燕舞[1] 王立学[1] 李清锋[1] 胡带翠[1] 陆皓[1] 

机构地区：[1]广西右江民族医学院附属医院,广西百色533000

出　　处：《包头医学院学报》2016年第8期33-34,共2页Journal of Baotou Medical College

摘　　要：目的:探究200名行CT血管造影术检查的患者使用非离子型对比剂对肾脏的临床影响。方法:选取在我院治疗的200例行64排CT血管造影检查的患者,将其随机分为观察组和对照组,各100例,其中观察组患者在行造影术前采取预防措施,对照组未采取预防措施。结果:对照组患者的对比剂肾病发病率及不良反应发生率高于观察组(P<0.05);对照组患者术后血清肌酐值高于术前(P<0.05),术后估算的肾小球滤过率低于术前(P<0.05)。结论:临床使用非离子型对比剂时应注意对患者的身体状况进行全面检查,采取有效的预防措施,以减少对比剂肾病等并发症的发生率。Objective： To explore the clinical influence of non-ionic contrast agents on kidneys of 200 patients that underwent CT angiography examination. Methods： 200 patients were chosen and randomly divided into the observation group and the control group,with 100 cases in each group. Preventive measures were taken before angiography in the observation group but not in the control group. Results： The morbidity rate of contrast nephropathy and adverse effects in the control group were higher than those in the observation group（ P〈0. 05）; the postoperative value of serum creatinine（ Scr） was higher than preoperative one of Scr in the control group（ P〈0. 05）; the estimated postoperative glomerular filtration rate（ e GFR） was lower than preoperative one（ P〈0. 05）. Conclusion： While non-ionic contrast agents are used for CT angiography,the patients must be examined thoroughly and effective measures must be taken so that the morbidity rate of complications such as contrast nephropathy will be reduced.

关 键 词：非离子型对比剂 肾脏 临床影响 

分 类 号：R816.7[医药卫生—放射医学]