弹性应变率比值法与声触诊组织量化技术联合诊断乳腺肿块的价值  

Effect of elastic strain rate ratio method and virtual touch tissue quantification on the diagnosis of breast masses

作　　者：宫丽杰[1] 贺焱[1] 田鹏[1] 闫妍[1] 

机构地区：[1]大庆油田总医院B超室,黑龙江大庆163001

出　　处：《中南大学学报（医学版）》2016年第7期729-735,共7页Journal of Central South University ：Medical Science

摘　　要：目的:探讨弹性应变率比值法与声触诊组织量化技术(virtual touch tissue quantification,VTQ)对乳腺肿瘤临床诊断准确性的价值。方法:选取大庆油田总医院乳腺外科接受手术治疗的60例女性乳腺肿瘤患者,患者知情同意后,对其依次进行常规超声检查、压迫式弹性成像(compression elastography,CE)检查、VTQ检查,CE检查取得应变率(strain ratio,SR)比值,VTQ测量剪切波的传播速度(shear wave velocity,SWV)值。并采受试者工作特征(receiver operating characteristic,ROC)曲线评价不同检查方法对乳腺肿瘤良恶性病变的诊断价值。结果:良性肿块的最大直径、SWV值均低于恶性肿块,良性肿块的SR比值高于恶性肿块,差异均具有统计学意义(P<0.01)。ROC曲线显示弹性应变率比值法与VTQ技术单用或联用的AUC、敏感性、特异性(分别为0.904,97.5%,69.2%;0.946,87.5%,87.2%;0.976,90%,97.4%)均高于常规超声(0.783,85%,61.5%);VTQ技术的AUC、特异性(0.946,87.2%)均高于弹性应变率比值法(0.904,69.2%),但其敏感性(87.5%)低于后者(97.5%);弹性应变率比值法与VTQ技术联用的AUC和特异性均高于两者单用,但其敏感性较弹性应变率比值法低。结论:弹性应变率比值法与VTQ技术联用的诊断价值优于二者单用。Obiective： To determine the effect of elastic strain rate ratio method and virtual touch tissue quantification （VTQ） on the diagnosis of breast masses. Methods： Sixty female patients with breast cancer, who received surgical treatment in Daqing Oilfield General Hospital, were enrolled. All patients signed the informed consent paperwork andthey were treated by routine ultrasound examination, compression elastography （CE） examination, and VTQ examination in turn. Strain ratio （SR） was checked by CE and shear wave velocity （SWV） value was measured by VTQ q-he diagnostic values of different methods were evaluated by receiver operating characteristic （ROC） curves in the diagnosis of benign and malignant breast tumors. Results： The maximum diameter and SWV value of the benign tumors were lower than those of the malignant tumors, and the SR ratio of benign masses was higher than that of malignant tumors （P〈0.01）. The AUC, sensitivity and specificity for elastic strain rate and VTQ for single or combined use were higher than those of conventional ultrasound （0.904, 97.5%, 69.2%; 0.946, 87.5%, 87.2%; 0.976, 90%, 97.4% vs 0.783, 85%, 61.5%）. q-he AUC and specificity ofVTQ were higher than those of the elastic strain rate （0.946, 87.2% vs 0.904, 69.2%）, but the sensitivity of VTQwas higher than that of the latter （87.5% vs 97.5%）. The AUC and specificity for combination of both methods were higher than those of single method, but the sensitivity was lower than that of the elastic strain rate. Conclusion： Combination of elastic strain rate ratio method with VTQ.possesses the best diagnostic value and the highest diagnostic accuracy in the diagnosis of breast mass than that used alone.

关 键 词：弹性应变率比值法 声触诊组织量化技术 乳腺肿块 鉴别诊断 

分 类 号：R445.1[医药卫生—影像医学与核医学]