Narcotrend和脑电双频指数用于异丙酚靶控输注麻醉深度监测的准确性比较  

Comparison of accuracy between Narcotrend and bispectral index(BIS)index used in propofol target-controlled infusion anesthetic depth monitoring

作　　者：何琼珍[1] 王富芬 李智[1] 王小虎[1] 

机构地区：[1]四川省广元市精神卫生中心麻醉科,628001

出　　处：《检验医学与临床》2016年第15期2149-2150,2152,共3页Laboratory Medicine and Clinic

摘　　要：目的比较Narcotrend(NT)和脑电双频指数(BIS)应用于异丙酚靶控输注(TCI)在无痛胃镜检查麻醉深度监测的准确性。方法选择90例接受无痛胃镜检查的患者,随机分为3组:对照组(常规给药组)、NT组(NT麻醉深度监测组)和BIS组(BIS麻醉深度监测组),每组各30例。3组患者均给予异丙酚TCI,并根据血流动力学参数、BIS值及NT值调整异丙酚的浓度。观察3组患者异丙酚总量、复苏时间、定向力恢复时间、生命体征及不良反应,并进行比较。结果 NT组和BIS组异丙酚总量、复苏时间、定向力恢复水平与对照组相比,均显著降低,且差异有统计学意义(P<0.05),NT组患者定向力恢复时间较BIS组降低,且差异有统计学意义(P<0.05)。3组患者平均动脉压(MAP)、心率(HR)、血氧饱和度(SpO_2)数值平稳,经麻醉后恢复到给药前水平。NT组和BIS组呼吸抑制、呛咳、体动和心动过速的发生率显著低于对照组(P<0.05)。结论 NT和BIS应用于异丙酚TCI在无痛胃镜检查中均可达到合理的麻醉深度,NT组患者定向力恢复水平优于BIS组。Objective To compare the accuracy of Narcoternd（NT） and bispectral index（BIS） used in propofol target‐controlled infusion（TCI） anesthetic depth monitoring in the painless gastroscopic examination .Methods A total of 90 patients with painless gastroscopy were selected and randomly divided into 3 groups：control group ,NT group（Narcotrend anesthetic depth monitoring） and BIS group（BIS nesthetic depth monitoring） ,30 cases in each group .The three groups were given propofol TCI ,moreover the propofol concentration was adjusted according to the hemodynamic variables ,NT and BIS values .The propofol total dose ,recovery time ,recovery time of orientation ,vital signs and adverse reactions were observed and compared among 3 groups .Results The propofol total dose ,recovery time and recovery level of orientation in the NT group and BIS group were obviously decreased com‐pared with the control group ,and the differences were statistically significant （P〈0 .05） .The recovery time of orientation in the NT group was decreased compared with the BIS group ,and the difference was statistically significant（P〈0 .05） .MAP ,HR and SpO2 in the three groups were stable and recovered to the level before medication after anesthesia .The incidence rates of respiratory depression ,bucking ,body movement and tachycardia in the NT group and BIS group were significantly lower than those in the con‐trol group （P〈0 .05） .Conclusion The application of NT and BIS in propofol TCI in painless gastroscopy can reach the rational anesthetic depth ,and the recovery level of orientation in the NT group is superior to that of the BIS group .

关 键 词：NARCOTREND 脑电双频指数 异丙酚 麻醉深度 准确性 

分 类 号：R169.42[医药卫生—公共卫生与预防医学]