三维径向应变评价早期慢性肾病患者左心室心肌收缩功能变化  

Three-dimensional Radial Strain in Evaluating the Changes of Left Ventricular Myocardial Contractional Function in Early Chronic Kidney Disease Patients

作　　者：刘开薇 任卫东[1] 孙璐[1] 宋光[1] 刘慧[1] 乔伟[1] 

机构地区：[1]中国医科大学附属盛京医院超声科,沈阳市110004

出　　处：《中国超声医学杂志》2016年第8期703-706,共4页Chinese Journal of Ultrasound in Medicine

基　　金：辽宁省科技厅科学技术计划项目(No.2013225049)

摘　　要：目的应用三维整体径向应变(GRS)评价早期慢性肾病(CKD)患者左心室心肌收缩功能。方法选取26例CKD 2期、20例CKD 3期患者及30例健康志愿者(对照组)。行常规二维超声心动图和三维斑点追踪成像(3D-STE),测量并比较常规超声心动图指标:室间隔舒张末期厚度(IVSTd)、左心室舒张末期内径(LVEDd)、舒张末期左室后壁厚度(LVPWTd)、舒张末期左心室容积(EDV)、收缩末期左心室容积(ESV)和3D-STE指标:左心室三维射血分(3D-LVEF)、三维左心室心肌质量指数(3D-LVMI)及左心室整体径向应变(GRS)差异。结果与对照组相比,CKD 2期的IVSTd增大,LVEDd、GRS减小;CKD 3期的IVSTd、LVESV、3D-LVMI显著增大,LVEDd、3D-LVEF、GRS显著减小;与CKD 2期相比,CKD 3期的IVSTd、3D-LVMI增大,LVEDd、GRS减小,以上差异均有统计学意义(P<0.05)。结论 CKD早期患者左心室心肌收缩功能已经减低,可通过GRS来评价。Objective To assess the changes of left ventricular myocardial contractional function in early chronic kidney disease（CKD）patients with three-dimensional global radial strain（GRS）.Methods 26 cases with CKD 2,20 cases with CKD 3and 30 healthy subjects as control group were enrolled in this study.Parameters were calculated and compared including two-dimensional echocardiography including left ventricular at end-diastole diameter（LVEDd）,interventricularseptal thickness at end-diastole（IVSTd）,left ventricular posterior wall thickness at end-diastole（LVPWTd）,end-diastolic volume（EDV）,end-systolic volume（ESV）and parameters of 3D-STE including three-dimensional left ventricular ejection fraction（3D-LVEF）,three-dimensional LV mass index（3D-LVMI）,and global radial strain（GRS）.Results Compared with the control group,in CKD 2group,IVSTd increased,LVEDd,GRS decreased;in CKD 3group,IVSTd,LVESV,3D-LVMI increased,LVEDd,3D-LVEF,GRS decreased.Compared with the CKD2 group,in CKD 3group,IVSTd,3D-LVMI increased,LVEDd,GRS decreased（P0.05）.Conclusions On the early stages of CKD,the left ventricular myocardial contractive function has reduced,which can be detected by 3DSTE with GRS.

关 键 词：超声心动描记术 三维 慢性肾病 心室功能 左 

分 类 号：R540.45[医药卫生—心血管疾病] R692[医药卫生—内科学]