螺旋CT灌注成像对肝细胞型肝癌与局灶性结节增生的鉴别诊断  

Differential diagnosis of hepatocellular carcinoma and focal nodular hy-perplasia by spiral CT perfusion imaging

作　　者：刘丽君[1] 

机构地区：[1]陕西省榆林市第二医院影像中心,陕西榆林719000

出　　处：《中国医药导报》2016年第22期117-120,共4页China Medical Herald

摘　　要：目的探讨螺旋CT灌注成像（CTPI）对肝细胞型肝癌与局灶性结节增生的鉴别诊断情况。方法分析陕西省榆林市第二医院2008年2月～2015年3月收治的120例肝细胞型肝癌患者和80例局灶性结节增生患者影像学资料，观察两组患者疾病实性部分及远处肝组织螺旋CT灌注参数情况，包括肝血流量（HBF）、肝血容量（HBV）、肝动脉灌注量（HAP）、总肝灌注量（TLP）、门静脉灌注量（PVP）、肝动脉灌注指数（HPI）、平均通过时间（MTT）。结果两组TLP差异无统计学意义（P〉0．05），局灶性结节增生HAP、HPI、MTT均高于肝细胞型肝癌．HBF、HBV、PVP低于肝细胞型肝癌，差异有统计学意义（P〈0．05）。肝细胞型肝癌病灶实性部HBF、HBV、HAP、HPI均高于远处肝组织，PVP、MTT低于远处肝组织，差异有统计学意义（P〈0．05）。局灶性结节增生病灶实性部分HBF、HBV、HAP、HPI均高于远处肝组织，PVP、MTT低于远处肝组织，差异有统计学意义（P〈0．05）。结论螺旋CT灌注成像可以反映肝细胞型肝癌与局灶性结节增生血流灌注特点，为肝细胞型肝癌与局灶性结节增生鉴别诊断提供可靠的理论依据。Objective To discuss the differential diagnosis of hepatocellular carcinoma and focal nodular hyperplasia by spiral CT perfusion imaging （CTPI）. Methods The image data of 120 cases with hepatocellular carcinoma and 80 cases with focal nodular hyperplasia in the Second Hospital of Yulin City from February 2008 to March 2015 were analyzed. The CT perfusion parameter including HBF, HBV, HAP, TLP, PVP, HPI, MTT of solid lesions and distance liver tissues were observed in the two groups. Results There was no statistically significant difference in TLP between the two groups （P 〉 0.05）. HAP, HPI, MTT than the focal nodular hyperplasia were higher than those in the hepatocellular carcinoma, and HBF, HBV, PVP were lower than the hepatocellular carcinoma, the differences were statistically significant （P 〈 0.05）. HBF, HBV, HAP, HPI in solid lesions of hepatocellular carcinoma were higher than those in the distance liver tissues, and PVP, MTT were lower than the distance liver tissues, with statistically significant differences （P 〈 0.05）. HBF, HBV, HAP, HPI in solid lesions of focal nodular hyperplasia were higher than those in the distance liver tissues, and PVP, MTT were lower than the distance liver tissues, with statistically significant differences （P 〈 0.05）. Conclusion CTPI can reflect the blood perfusion characteristics of hepatocelluiar carcinoma and focal nodular hyperplasia, which can provide reliable theory basis for differential diagnosis of hepatocellular carcinoma and focal nodular hyperplasia.

关 键 词：螺旋CT灌注成像 肝细胞型肝癌 局灶性结节增生 鉴别诊断 

分 类 号：R814.42[医药卫生—影像医学与核医学]