复方芦荟丸剂醇提取工艺的优化  

Optimization on alcohol extraction process of Compound aloe pills

作　　者：孟婷婷[1] 刘杨[1] 袁勇[2] 

机构地区：[1]石河子大学药学院,新疆石河子832002 [2]石河子大学医学院第一附属医院,新疆石河子832008

出　　处：《农垦医学》2016年第2期122-124,共3页Journal of Nongken Medicine

基　　金：国家自然科学基金项目(81460638)

摘　　要：目的:优选复方芦荟丸的提取工艺。方法:以芦荟苷为对照品,采用HPLC法测定芦荟中芦荟苷的含量。采用正交试验设计,以芦荟苷的含量及出膏率为综合指标,考察醇浓度、加醇倍量、提取次数及提取时间的影响。结果:最佳提取工艺为以生药10倍量的70%乙醇回流提取2次,每次1h。结论:该提取工艺合理、稳定、可行,为复方制剂的制备工艺提供了科学依据。Objective：To optimize alcohol extraction process of compound aloe pills.Methods：Aloin as reference to determine the content of aloevera glycosides by HPLC.It was investigated at alcohol concentration,the amount of alcohol,extraction times and extraction time,with aloin and a comprehensive cream as index by orthogonal experimental design.Results：The optimum extraction of crude drug 10 times the amount of 70% ethanol was extracted two times,each time 1h.Conclusion：The extraction process is reasonable,stable and viable to provide a test basis for compound preparation

关 键 词：芦荟 提取工艺 高效液相色谱法 

分 类 号：R965.2[医药卫生—药理学]