血栓通治疗地震后肺挫伤临床疗效的回顾性研究  

Efficacy of Xueshuantong injection for pulmonary contusion caused by earthquake

作　　者：马天洪[1] 李德志[1] 于白莉[1] 覃渝茜[1] 

机构地区：[1]成都中医药大学附属医院骨科,四川成都610075

出　　处：《西部医学》2016年第8期1142-1146,共5页Medical Journal of West China

基　　金：国家中医药管理局科研项目(ZY1C20140303)

摘　　要：目的探讨血栓通结合西医治疗对地震后肺挫伤的临床疗效。方法采用回顾性研究,收集35例5.12地震肺挫伤病例,按不同的治疗方案分为两组,标准西医基础治疗上辅以三七皂苷提取物即血栓通注射液的患者纳入常规西医加血栓通注射液治疗组,病例数18例,标准西医基础治疗组纳入常规西医治疗组,病例数17例,对比两组治疗前、治疗后1周、2周机械通气治疗的使用情况及机械通气治疗时间、血氧饱和度和平均住院时间。结果常规西医加血栓通注射液治疗组与常规西医治疗组随着时间增加,肺部阴影面积减小(P=0.034,P=0.015),不同分级患者机械通气带机时间缩短(P=0.020,P=0.046),住院时间减少。西医加血栓通治疗组在促进肺部阴影吸收、缩短机械通气治疗患者的带机时间、住院时间与西医治疗组比较差异有显著统计学意义(P=0.021,P=0.037,P=0.028)。结论血栓通结合常规西医治疗有利于肺挫伤恢复,缩短住院时间,减少呼吸机的使用。Objective To analyze the efficacy of combination of western medicine plus Xueshuantong Injection in treatment of pulmonary contusion caused by Wenchuan earthquake. Methods 35 pulmonary contusion patients were enrolled and simple treatment of western medicine （n= 17） and western medicine plus Xueshuantong injection （n= 18） were conducted, respectively. Oxygen saturation in arterial blood and the change of thoracic X-Ray were measured at baseline, one week and two weeks. The use of mechanical ventilation and durations of mechanical ventilation and hospital stay were also recorded. Results Compared with simple treatment of western medicine group, the western medicine plus Xueshuantong injection group was superior in the change of thoracic X-Ray （P=0. 034, P=0.15）, durations of mechanical ventilation（P=0. 020,P=0. 046） and hospital stay（P=0. 021,P=0. 037,P=0. 028）. Conclusion Western medicine plus Xueshuantong injection can shorten the durations of hospital stay, reduce the use of mechanical ventilation, and be conducive to the recovery of pulmonary contusion.

关 键 词：血栓通注射液 地震 肺挫伤 回顾性研究 

分 类 号：R655.1[医药卫生—外科学]