浅析原发性醛固酮增多症中肾上腺醛固酮瘤和特发性醛固酮增多症的临床特点  

Analysis of the Clinical Features of Adrenal Aldosterone Tumor and Idiopathic Aldosterone in Patients with Primary Aldosterone

作　　者：赵伟军 

机构地区：[1]江苏省常州市新北区春江人民医院内科,江苏常州213000

出　　处：《中国继续医学教育》2016年第18期133-134,共2页China Continuing Medical Education

摘　　要：目的 研究分析原发性醛固酮增多症中肾上腺醛固酮瘤和特发性醛固酮增多症的临床特点。方法 选取2015年7-12月我院内分泌科所收治的肾上腺醛固酮瘤患者16例作为本研究观察组研究对象,12例特发性醛固酮增多症患者作为对照组,对比分析两组患者的临床特点。结果 观察组患者与对照组患者血钾、尿钾、尿醛固酮以及血醛固酮水平分别为：（2.44±0.37）mmol/L、（51.25±28.93）mmol/L、（55.45±28.93）nmol/L、（1240.94±783.37）pmol/L与（2.96±0.42）mmol/L、（59.83±29.01）mmol/L、（40.24±21.07）nmol/L、（709.21±546.62）pmol/L。肾上腺醛固酮瘤与特发性醛固酮增多症相比,其基础血醛固酮水平以及尿醛固酮水平均明显更高,而血钾水平则相对更低,差异具有统计学意义（P〈0.05）。结论 肾上腺醛固酮瘤生化异常相对来讲,其特征更加明显,可在临床上广泛的推广应用。Objective To study the clinical characteristics of adrenal aldosterone tumor and idiopathic aldosterone in patients with primary aldosterone. Methods 16 cases with aldosterone-producing adenoma from July to December 2015 were selected as observation group, and 12 cases with idiopathic aldosterone gain were selected as control group. Clinical characteristics of two groups were compared. Results Lack the main results of the study data： patients in the observation group and the patients in the control group, serum potassium, potassium in the urine and urinary aldosterone and plasma aldosterone levels respectively： （2.44±0.37）mmol/L, （51.25±28.93） mmol/L, （55.45±28.93）nmol/L, （1240.94±783.37） pmol/L and （2.96±0.42） mmol/L, （59.83±29.01）mmol/L, （40.24±2.107） nmol/L, （709.21±546.62） pmol/L. Adrenal aldosterone producing adenoma and idiopathic hyperaldosteronism increased compared. The serum aldosterone levels and urinary aldosterone levels were significantly higher, and serum potassium level is relatively lower, and the difference was statistically significant （P〈0.05）. Conclusion The biochemical abnormalities of adrenal aldosterone tumor is relatively speaking, its characteristics are more obvious, which can be widely used in clinical practice.

关 键 词：肾上腺醛固酮瘤 特发性醛固酮增多症 临床特点 诊断 

分 类 号：R586.24[医药卫生—内分泌]