CTA评价冠状动脉粥样硬化管腔狭窄程度及其高危因素的相关性  

Computed tomography angiography(CTA) study on coronary atherosclerosis stenosis in risk factors asymptomatic population

作　　者：刘烨[1] 王耀彬[1] 陈天金[1] 温友信 韩向东[1] 杨立[2] 

机构地区：[1]武警北京总队第二医院放射科,100037 [2]解放军总医院放射科,北京100853

出　　处：《武警医学》2016年第7期666-668,671,共4页Medical Journal of the Chinese People's Armed Police Force

摘　　要：目的应用冠状动脉CT血管成像(computed tomography angiography,CTA)确定有高危因素且非糖尿病无冠心病症状者冠状动脉粥样硬化(coronary atherosclerotic,CA)管腔狭窄程度,评价其与高危因素的相关性。方法在非糖尿病无冠心病症状健康查体的人群中,收集有高危因素(性别、年龄、高血压、高脂血症)者,并将其分为单项高危因素组、多项高危因素(2项及以上高危因素)组。统计有高危因素者冠状动脉粥样硬化管腔狭窄程度。结果单项及多项高危因素各组,管腔狭窄程度为Ⅰ级的发病率最高,随年龄的增长,管腔狭窄程度为Ⅱ级、Ⅲ级的发病率也增长。有高危因素且冠状动脉粥样硬化管腔狭窄>50%者与对照组对比,单项高危因素且>40岁组及多项高危因素各组,冠状动脉粥样硬化管腔狭窄>50%的发生率与对照组有显著差异(P=0.0011,P=0.048,P=0.020);单项高危因素且<40岁组,管腔狭窄>50%的发生率与对照组无显著差异(P=0.6013)。结论在非糖尿病无症状人群中,冠状动脉CTA在预测冠状动脉病粥样硬化严重程度方面提供重要的信息。Objective To make use of coronary CTA to determine the incidence rate of coronary atherosclerosis stenosis for non-diabetic asymptomatic people who have risk factors and evaluate its correlation with risk factors. Methods We recruited non-diabetic asymptomatic people who have high-risk factors（ sex,age,hypertension,hyperlipidaemia） and divided them into single high-risk factor group and multiple high-risk factors group. We made statistical processing on the incidence rate of disease for people who had high-risk factors of coronary atherosclerosis. Results Single and multiple high risk factors between groups,the degree of luminal stenosis rate was highest for grade Ⅰ; along with increasing age,the incidence of class Ⅱ,Ⅲ grade luminal stenosis grew. Risk factors and coronary atherosclerosis luminal stenosis 50% compared with the control group,single risk factors and 〉40 years old and multiple risk factors group,incidence of coronary atherosclerosis luminal stenosis 〉50% had significant differences from the control group（ P =0. 0011,P = 0. 048,P = 0. 020）. single risk factors and〈 40 years old groups,the incidence of coronary atherosclerosis luminal stenosis 50% had no significant difference from the control group（ P = 0. 6013）. Conclusions In asymptomatic non-diabetic population,coronary CTA in the prediction of atherosclerotic coronary artery disease severity provides important information. A large number of clinical data showed that coronary CTA can display plaque number and number of luminal stenosis ≥50%.

关 键 词：冠状动脉粥样硬化管腔狭窄 CT血管成像 危险因素 

分 类 号：R541.4[医药卫生—心血管疾病]