开放性骨折患者创面感染的病原菌分布与药敏分析  

Pathogenic bacteria distribution and drug resistance in wound infected patients with open fracture

作　　者：刘立柱 宋世锋 张伟 李超艺 李强 

机构地区：[1]海南省农垦总医院骨三科,海南海口570311

出　　处：《中华医院感染学杂志》2016年第15期3505-3507,共3页Chinese Journal of Nosocomiology

基　　金：海南省自然科学基金资助项目(30715)

摘　　要：目的研究开放性骨折患者创面感染的病原菌分布及药敏分析,为降低感染率提供参考依据。方法选择2012年1月-2015年6月医院出现创面感染的开放性骨折患者160例,对分离出的病原菌进行鉴定,探讨开放性骨折患者创面感染的病原菌分布与耐药性,数据采用SPSS 17.0软件进行统计分析。结果 160例感染患者共分离出160株病原菌,以革兰阳性菌为主,共78株占48.75%,革兰阴性菌60株占37.50,真菌22株,占13.75%;革兰阳性菌对氨苄西林/舒巴坦耐药性高,均为100.0%,对呋喃妥因、万古霉素和替考拉丁的耐药性较低,均为0。结论开放性骨折患者创面感染的病原菌以革兰阳性菌为主,应加强无菌操作,合理使用抗菌药药物。OBJECTIVE To study the distribution of pathogenic bacteria and drug sensitivity of wound infection in open fracture patients,so as to reduce infection rate.METHODS A total of 160 wound infected patients with open fractures from Jan.2012 to Jun.2015 were selected.The pathogenic bacteria were isolated and identified,and the pathogenic bacteria distribution and drug resistance of wound infection in open fracture patients were explored.The data were analyzed by SPSS 17.0.RESULTS Totally 160 strains of pathogenic bacteria were isolated from 160 cases of infected patients,including 78 strains of gram-positive bacteria,accounting for 48.75%,60 strains of gram-negative bacteria,accounting for 37.5%,and 22 strains of fungi,accounting for 13.75%.The drug resistant rates of gram-positive bacteria to ampicillin/sulbactam were high which were 100%,and low to nitrofurantoin,vancomycin and teicoplanin,which were 0.CONCLUSIONThe pathogenic bacteria of open fracture patients with wound infection were mainly gram-positive bacteria.It should strengthen aseptic operation,and rational use of antimicrobial drugs.

关 键 词：开放性骨折 创面感染 病原菌 耐药性 

分 类 号：R181.32[医药卫生—流行病学]