肝移植术后宫腔内人工授精成功妊娠并足月分娩一例及文献复习  

Successful Pregnancy and Term Delivery in a Liver Transplant Patient Following Intrauterine Insemination: Case Report and Review

作　　者：林凯璇[1] 周秋明[1] 李鸿儒[2] 吴元赭[1] 

机构地区：[1]南京军区南京总医院妇产科,210002 [2]南京军区南京总医院生殖医学中心,210002

出　　处：《国际妇产科学杂志》2016年第4期403-406,共4页Journal of International Obstetrics and Gynecology

摘　　要：肝移植是终末期肝脏疾病患者的最终选择。大部分生育年龄的女性患者接受肝移植后能很快恢复正常生活,并希望养育后代。通过自然受孕并顺利分娩的患者并不少见,但仍有部分患者因为各种原因出现不孕。关于不孕的器官移植后患者接受辅助生殖技术(assisted reproductive technology,ART)实现妊娠的报道极少,因为这不仅涉及到复杂的伦理问题,而且需要多个学科间的联合协作。ART的目的必须以健康妊娠为前提,最大限度地降低母体和胎儿并发症。本文介绍了1例不孕的肝移植术后患者,经过宫腔内人工授精(intrauterine insemination,IUI)成功妊娠并足月分娩,探讨妊娠对移植肝脏的影响及免疫抑制剂和肝移植对妊娠的影响。Liver transplantation is the final choice of the end-stage liver disease. Most of childbearing age women regainto normal life, hoping to bring up offspring. Although quite a few of these patients get conception and delivery without a hitch,still portion of them are infertile because of all kinds of reasons. Cases about infertile patients who had accepted assistedreproductive technology （ART） after organ transplantation are rare, since these not only refer to complicated ethical nature, butalso require multi -disciplines collaboration. ART premises healthy pregnancy as well as minimizes maternal and fetalcomplications. This review introduced a case that a liver transplant patient who succeeded to be pregnant following intrauterineinsemination and delivered at full-time, and also discusses the influences among graft, pregnancy and immunosuppressor.

关 键 词：肝移植 授精 人工 生殖技术 辅助 妊娠 伦理学 医学 

分 类 号：R714.8[医药卫生—妇产科学]