不同营养状况对慢性阻塞性肺疾病患者运动耐力和生活质量的影响  

Effect of different nutrious status on exercise capacity and quality of life in patients with chronic obstructive pulmonary disease

作　　者：王月霞[1] 刘豹[1] 雪平[1] 王卫香[1] 

机构地区：[1]郑州大学人民医院呼吸内科,450003

出　　处：《中国实用医刊》2016年第15期1-4,共4页Chinese Journal of Practical Medicine

基　　金：2013年河南省医学科技攻关项目（201303143）

摘　　要：目的：利用生物电阻抗技术探讨体成分指标与稳定期慢性阻塞性肺疾病（ COPD）患者运动耐力和生活质量之间的关系。方法采用横断面调查的方法，对33例稳定期COPD男性患者进行一般资料、人体成分分析、肺功能检查、6 min步行试验、呼吸困难分级及COPD评估测试的调查，计算BODE指数，对其结果进行相关性分析。并将COPD患者按照体质量指数（ BMI）分为BMI正常组、超重组和肥胖组进行单因素方差分析，观察三组间COPD相关评价指标的差异。结果体质量指数、脂肪质量指数（FMI）、去脂体质量指数（FFMI）、身体水分质量指数（BFMI）、肌肉质量指数（ SMMI）与第1秒用力呼气容积占预计值百分比（ FEV1%）呈正相关，与BODE指数呈负相关；身体水分率、肌肉率与FEV1%呈负相关，与BODE指数呈正相关；体脂肪率与BODE指数呈负相关。BMI正常组、超重组和肥胖组三组间FMI、FFMI、BFMI、SMMI、蛋白质质量指数（PMI）比较差异均有统计学意义（P﹤0.01）。三组间COPD相关评价指标比较差异未见统计学意义（ P﹥0.05）。结论体成分指标与身高和体质量结合计算之后，与稳定期COPD患者运动耐力和生活质量之间高度相关。超重和肥胖对COPD患者运动耐力和生活质量可能无有害影响。Objective To investigate the relationship between body composition indexes and exer-cise capacity,quality of life in patients with chronic obstructive pulmonary disease（ COPD）in stable stage. Methods A simple sampling survey of 33 COPD patients in stable stage was enrolled. Patients had body composition analysis,pulmonary function tests,6MWT,and health status was evaluated with mMRC and CAT. The COPD patients were divided into normal BMI group,overweight group and obesity group accord-ing to BMI,and then the differences of indexes among the three groups were observed. Results Body mass index（ BMI）,fat mass index（ FMI）,fat free mass index（ FFMI）,body fluid mass index（ BFMI）and skeletal muscle mass index（ SMMI）was positively correlated with FEV1%,and was negatively correlated with BODE index. Body moisture rate and skeletal muscle rate,was negatively correlated with FEV1%, and was positively correlated with BODE index. Fat rate was negatively correlated with BODE index. There were significant differences in FMI,FFMI,BFMI,SMMI,PMI among the three groups（P﹤0. 01）. There was no significant difference in COPD associated indexes among the three groups（ P ﹥0. 05 ）. Conclusions When the body composition indexes,height,and weight is taken into account,they are highly correlated with exercise capacity,quality of life in COPD patients in stable stage. There seems to be no harmful effects of overweight and obesity on the exercise capacity and quality of life in COPD.

关 键 词：体成分指标 慢性阻塞性肺疾病 运动耐力 生活质量 

分 类 号：R563.05[医药卫生—呼吸系统]