双链季铵盐复合邻苯二甲醛消毒液研制及比较  

Development and comparison of ortho-phthalaldehyde disinfectant by compounded double chain quaternary ammonium salts

作　　者：薛佳(馬坴) 严万春 薛仲华[3] 

机构地区：[1]上海天坛助剂有限公司,上海201419 [2]上海桑迪精细化工研究所有限公司,上海200025 [3]华东理工大学化学与分子工程学院,上海200237

出　　处：《工业微生物》2016年第4期29-33,共5页Industrial Microbiology

摘　　要：通过将邻苯二甲醛、双链季铵盐与相应助剂进行复配,制备一种新型的复合消毒剂,并进行灭菌消毒试验、清洗效果及稳定性试验。实验证明邻苯二甲醛复合消毒剂浓度在2 000 mg/L时对白色念珠菌的杀灭效果达100%。该复合消毒剂原液经45℃恒温放置15 d,邻苯二甲醛的下降率为2.26%左右,稳定性和杀菌能力有明显提高。对油脂清洗率达98%以上,具有消毒清洗双功能。因此邻苯二甲醛复合消毒剂对消化内镜消毒灭菌效果高,耗时短,用法简便,并可降低对医务人员健康的危害性,是值得在医院临床推广使用的高效消毒剂。A new compound disinfectant was prepared by combining o-phthalaldehyde, double chain quaternary ammonium salt and auxiliary chemicals. The experiments showed that the germicidal efficacy of the compound disinfectant on Candida albicans was 100% at the concentration of 2 000 mg/L. Under the conditions of at 45 ℃ for 15 days, the ortho-phthalaldehyde decline rate of compound disinfectant was about 2 . 26%, stability and sterilization ability was obviously improved. Fats cleaning rate exceeded 98%. So it had a dual function of disinfection and cleaning. The use of the compound disinfectant of ortho-phthalaldehyde had high efficiency,shorter germicidal time and convenient usage, and less harm to medical personnel. Therefore, it is worth to use in the hospital clinical operations.

关 键 词：邻苯二甲醛 双链季铵盐 戊二醛 消化内镜 白色念珠菌 消毒效果 

分 类 号：TQ421[化学工程]