丙泊酚复合利多卡因在腹腔镜胆囊切除术中的麻醉效果及对股静脉血流动力学的影响  

EFFECT OF PROPOFOL COMBINED WITH LIDOCAINE ON HEMODYNAMICS IN THE ANAESTHETIC OF LAPAROSCOPIC CHOLECYSTECTOMY

作　　者：刘德民[1] 巨长桥[1] 李莲娣[1] 

机构地区：[1]黑龙江省牡丹江医学院第二附属医院,牡丹江157011

出　　处：《广西医科大学学报》2016年第4期623-625,共3页Journal of Guangxi Medical University

基　　金：黑龙江省卫生计生委科研课题资助项目(No.2014-202)

摘　　要：目的：探讨静脉连续输注丙泊酚复合硬膜外利多卡因麻醉在腹腔镜胆囊切除术（LC）中的临床效果及对股静脉血流动力学的影响。方法：收集黑龙江省牡丹江医学院第二附属医院2014年2月至2016年2月收治的ASAⅠ~Ⅱ级、行LC患者120例,随机分为对照组和观察组,每组各60例,对照组给予单一静脉连续输注丙泊酚进行麻醉处理后完成LC,观察组给予静脉连续输注丙泊酚复合硬膜外利多卡因麻醉处理后完成LC,记录并对比两组患者意识恢复时间、拔管时间以及止痛时间作为麻醉效果评价指标,同时采集两组患者气腹状态和意识恢复状态5min时股静脉血流速度、流量数据。结果：观察组的意识恢复时间,拔管时间以及止痛时间均显著短于对照组（P〈0.01）,且气腹状态和意识恢复状态5min时股静脉流量、股静脉流速均显著高于对照组（P〈0.01或P〈0.05）。结论：静脉连续输注丙泊酚复合硬膜外利多卡因麻醉在LC中的临床效果显著优于单一丙泊酚静脉连续输注麻醉,且对股静脉血液的阻滞作用较小,值得临床推广应用。Objective： To study the effects of continuous intravenous propofol infusion combined with epidurallidocaine injection on hemodynamics in the anaesthetic of laparoscopic cholecystectomy. Methods： 120cases of ASA class I ,II patients undergoing laparoscopic cholecystectomy in our hospital from February2014 to February 2016 were randomly divided into the control group and the observation group （60 casesper group）. The patients in the control group were anaesthetize by continuous intravenous infusion ofpropofol, while those in the observation group were anaesthetize by continuous intravenous infusion ofpropofol and epidural lidocaine injection. The time of consciousness recovery, tube drawing and analgesiawere measured and evaluated for the anaesthetic effects. The blood flow rate and velocity of femoral veinwere recorded at the pneumoperitoneum states and re-consciousness. Results： The time of consciousnessrecovery, tube drawing and analgesia in the observation group were significantly less than those in the controlgroup （ P 〈0. 01）. The blood flow rate and velocity of femoral vein in the observation group were significantlyhigher than those in the control group （ P 〈 0. 01 or P 〈0. 05）. Conclusion： The use of continuousintravenous propofol infusion in combination of epidural lidocaine injection for patients undergoing laparoscopiccholecystectomy is better than the simple continuous intravenous infusion of propofol, with a lessblood flow blocking effect. Therefore, this combination is worthy for clinical promotion.

关 键 词：丙泊酚 利多卡因 复合麻醉 腹腔镜胆囊切除术 

分 类 号：R656.06[医药卫生—外科学]