运用MRI T2-mapping动态观察埋植线体对正常人体经穴刺激效应的特点  

Stimulating effects of embedded material on acupoints in healthy human using MRI T2-mapping scanning over time and location

作　　者：聂红昉[1] 梁欣[2] 侯珣瑞 

机构地区：[1]贵州医科大学附属医院影像科,贵州550004 [2]贵州医科大学附属医院针灸科

出　　处：《北京中医药大学学报》2016年第7期605-609,共5页Journal of Beijing University of Traditional Chinese Medicine

基　　金：贵州省中医药管理局项目(No.QZYY2013-86)

摘　　要：目的动态观察微创埋线后线体对正常人体不同穴位刺激效应的变化特点及其差异性,为微创埋线疗法间隔周期提供参考依据,并探讨磁共振成像(MRI)T2-mapping技术在观察穴位埋植后埋植材料对人体经穴刺激效应的可行性。方法采集8例正常人体左侧三阴交、足三里埋线前、后多个时间点T2-mapping 8回波序列MRI图像,将所得8回波系列图像利用Func Tool软件生成T2-Mapping图像,测量埋线局部T2值,分析埋线前、后多个时间点埋线局部T2值随时间变化的特点,比较埋植线体在三阴交和足三里穴中吸收状况。结果与埋线前相比,2穴埋线后第8小时、第3天、第7天、第14天的T2值皆明显升高(P<0.01);埋线后第21天、第28天、第35天的T2值与埋线前比较均无明显差异(P>0.05)。埋线后2穴T2值峰值均出现在埋线后第3天,其中足三里穴T2值峰值较三阴交穴高,T2值下降幅度较三阴交穴大,但2穴T2值下降至接近埋线前的时间周期基本一致,均为21 d左右。结论三阴交穴、足三里穴微创埋线后,线体在2穴内吸收周期无显著差异,均为21 d左右,相同埋线条件下,在人体四肢部实施微创埋线时埋线间隔周期的选择可以此为参考。MRI T2-mapping技术用于观察穴位埋植后埋植线体对人体刺激效应具有一定的应用价值。Objective To observe changes in the stimulating effects of micro-invasion catgut embedding on different aeupoints in healthy human over time and location, providing reference data for interval peri- od of micro-invasion catgut embedding, and To study the feasibility of MRI T2-mapping technology used to measure stimulating effect of embedding material. Methods Before and after the left acupoints sanyin-fiao （SP 6） and zusanli （ST 36） were treated with micro-invasion catgut embedding on 8 healthy sub- jects, 8 echo sequence images were collected by using MRI scan. Sources of 8-echo sequence images were sent to the work station to get T2-mappings, and test the T2 value on T2-mappings, analyzing the characteristics of T2 value with time variation while comparing the difference of catgut absorption in SP 6 and ST 36. Results In both two acupoints,T2 values on the 8th hour, the 3th, the 7th and the 14th day after being catgut-embedded were all higher than those at the time before catgut-embedding （P 〈 0.01 ）, T2 valuse on the 21th, the 28th and the 35th day after being catgut-embedded presented with no significant difference compared with the time before catgut-embedding （ P 〉 0.05 ）. After being catgut-embedded, the peaks of T2 value appeared on the 3th day. Peak of T2 value in ST 36 was higher than that in SP 6, and T2 value in ST 36 decreased in a curve steeper than that in SP 6. It both took 21 days for T2 value in two acupoints to decrease to the level before catgut-embedding. Conclusion Catguts absorption peri- od in ST 36 and SP 6 are the same. If applying micro-invasion catgut-embedding in acupoints on normal body limbs at the same condition, the catgut-embedding interval period is probably about 21 days. MRI T2-mapping technology could be applied to observe stimulating effect of embedding material after acupoint embedding.

关 键 词：埋植线体 正常人体经穴 刺激效应 线体吸收周期 磁共振成像r112图 

分 类 号：R245.91[医药卫生—针灸推拿学]