Beers标准联合STOPP/START准则评价我院内科老年住院患者潜在不适当用药  

Evaluation of Potentially Inappropriate Medication among Elderly Inpatients in Internal Medicine Department of Our Hospital by Beers Criteria and STOPP/START Criteria

作　　者：周海峰[1] 沈杰[1] 纪芳[1] 张云轩[1] 张敏[1] 

机构地区：[1]复旦大学附属华东医院药剂科,上海200040

出　　处：《中国药房》2016年第23期3212-3214,共3页China Pharmacy

摘　　要：目的:提高合理用药水平,减少潜在不适当用药。方法:以Beers(2012年版)标准联合STOPP/START准则对我院内科700例老年住院患者用药潜在风险进行评价。结果:700例患者平均年龄(76.3±7.2)岁,平均用药(12.1±4.9)种,有144例(20.6%)存在潜在不适当用药;共计存在潜在不适当用药220例次,其中Beers药物相关117例次、Beers疾病相关22例次、STOPP用药9例次、START处方遗漏72例次。Beers审核结果中潜在不适当用药频度最高的药物为苯二氮类,STOPP审核结果频度最高的是有痛风史的患者使用噻嗪类利尿药;START处方遗漏频度最高的是2型糖尿病未接受二甲双胍治疗和糖尿病有心血管风险未接受抗血小板治疗。结论:我院老年住院患者潜在不适当用药情况较严重,应采取多种措施预防其不合理用药。OBJECTIVE：To improve rational drug use and reduce potentially inappropriate medication（PIM）. METHODS：PIM of 700 elderly inpatients in internal medicine department of our hospital was evaluated by Beers criteria（2012 edition）and STOPP/START criteria. RESULTS：700 inpatients whose mean ages were（76.3±7.2）years old took（12.1±4.9）kinds of drugs per patient. 144 cases involved PIM（20.6%）. The number of PIM was 220 in total,among which there were 117 cases/times related to drugs and 22 cases/times related to disease in according to Beers criteria,9 cases/times of STOPP and 72 cases/times of START. Drug with most frequency of PIM in accordance with Beers was benzodiazepines and most frequency in STOPP was thiazides that used by patients with gout histonry. The most omission frequency of START prescription were absence of metformin therapy for type 2 diabetes and absence of antiplatelet therapy for diabetes complicated with cardiovascular risk. CONCLUSIONS：A high prevalence of PIM in elderly inpatients in our hospital requires various measures to prevent its occurrence.

关 键 词：Beers标准 STOPP/START准则 老年患者 潜在不适当用药 

分 类 号：R969.3[医药卫生—药理学] R952[医药卫生—药学]